diseasereprieve

Chapter l:

PURELY PERSONAL

Twenty-five years ago, with a history of 6 PVC’s per minute, Meniere’s Syndrome, 40 pounds overweight, an aversion to high altitudes, and 45,000 micromhos of Total Dissolved Solids in my plasma and urine, I had reached a disturbing curtailment of my physical activities.

A respiration rate in excess of 45 beats per minute, Tachycardia and Precordial pain … all were symptoms obvious to 15 other Physicians during the Annual Meeting of the Society of Endocrinology & Nutrition in Breckenridge, Colorado. All agreed on a diagnosis: Anoxia, secondary to altitude at 12,000 feet. All agreed I would be okay when I returned to Cincinnati’s 400 ft. elevation.

A mirror reflected myself 55 pounds overweight, with hemorrhoids, premature baldness, motion sickness so acute as to discourage flying and deep sea fishing, or even riding in a car as a passenger. All symptoms were screaming for my attention; sending a call for help.

My then state-of-ability as a physician was incomplete. My physical and mental health was in serious medical compromise. As a result I did what I was subconsciously trained to do:

I saw a SPECIALIST!

I sought advice from two highly competent physicians, an MD and a D.O. A thorough vascular work-up followed. I respected each of them then and I respect them now; each gave me the best of his training and experience.

‘What do you make of my 6 PVC’s per minute?’, I asked. ‘Oh, we see this frequently in men your age’, was the gist of his reply.

‘How about Digitalis?’, I probed, fully realizing I would be smarter to keep quiet!

‘Not necessary’, he said. ‘Won’t help’, he added. ‘How about Quinidine Sulfate?’, I queried, my anxiety increasing.

‘Not at this time: maybe later’, he calmly answered. ‘Should I stop jogging?’, I asked, my anxiety now totally unconcealed.

His answer: ‘You know more about jogging than I do. Let’s do nothing’, said one.

‘Let’s just ‘watch it’, said the other.

The rumbling inside my chest drowned out any effective advice offered. One consolation raced through my mind: I’ll get another opinion! This time I’ll see a D.O.—a specialist of my own School of Medicine.

Four hours later, with yet another thorough physical examination under my belt, my disenchantment was unchanged. You would have thought they had jointly examined me and used the same health bulletin from which to make a diagnosis.

I had driven only a few miles on the interstate when I bolted to attention at the voice on the radio saying:

We interrupt this program to bring you a news update on the cause of the crash in which 263 passengers lost their lives. Federal Aviation Authorities have determined the cause of the crash.

Emotionally waxing and waning between anger and fear, the irony was inescapable. The U. S. Civil Air Agencies can determine the cause of an airline crash, but U. S. Physicians cannot tell me WHY I’m having skipped heartbeats! One effort was to locate the cause; another was to ignore the cause.

I wondered how airline passengers would react to a message from the Captain:

‘Ladies and Gentlemen, the engines are misfiring 5 or 6 times

per minute, but do not be concerned. Have a nice flight!’

I returned to reality and reflected on a recent sentence someone had penned, designed to motivate:

IF IT IS TO BE, IT IS UP TO ME.

This was the beginning of a serendipitous experience I cannot explain or understand.

No attempt is implied here to denigrate the finest Internist I could find. His credentials demanded and got my respect. While I later found reason and logic to disagree with his regimen, it would lead me to bold action, get me away from the mainstream of medicine and propel me from tunnel vision to wide-angle vision.

Maybe there is more to be learned about Cardiovascular Disease than is currently known, I thought. I made an immediate decision.

I WILL GO ANYWHERE

PAY ANY PRICE

DO ANYTHING NECESSARY

to find an answer to my problem. Truly, if it was to be, it was up to me.

If this happened in 1997 and I did not have a high resistance to intimidation, I would have been in surgery for an immediate by-pass. It was a revelation: these ‘specialists’ knew no more than I did about Cardiovascular diseases, and that was a frightening thing!

At age 56, a widower with four beautiful children to rear, my options were few. I had but six years to go before reaching my father’s age when he suffered a fatal Coronary Occlusion.

An inordinately high number of physical symptoms that led to my father’s loss of life were present within me. Like father, like

son. The staccato of my irregular heartbeat was persistently annoying. Family obligations compelled me to find a solution—and find it quickly!

Chapter 2:

THE ODYSSEY

In 1968 I closed my practice and began an odyssey, which led me through medical academia, libraries and seminars within and without the so-called mainstream of medicine. I was searching for a true understanding of the fundamental cause of Cardiovascular-Renal Disease.

My first stop on the journey took me to Roanoke, Virginia, where a physician from England was holding a seminar on animal and human pathology. The chemistry of water, the Total Dissolved Solids in the water, and the electrolytes of human and animal plasma seemed innocuous and almost made me pass up the course. How could there be a relationship between water and heart disease?

How could there be minerals in the water harmful to the human body? After all, didn’t we get our needed minerals from drinking water? The answer: A huge emphatic NO!

Essential minerals are not within our drinking water. If so, would we seek the essential minerals in the presence of such lethal elements as Lead, Arsenic, Aluminum, Mercury and Zinc to name but a few.

Inorganic minerals found in lakes, rivers, streams and city water systems are a primary source of toxicity to human and animal life. For further information read Rachel Carson’s revealing treatise Silent Spring.

The diversified training of a Generalist demands wide-angle vision in order to be effective in aiding his/her patients to undergo the personal growth necessary to understand and cope with the assortment of maladies that happen in life.

The wide-angle vision amplifies the resources available for training patients to identify and avoid direct causes of many diseases. What you perceive and believe determines your course of action.

All of us have to fight our own Resistance to Change factor. The RC Factor seems to be innate. Ironically, the more educated we are the most fixed is our belief and the greater our Resistance to Change.

Medical professionals are frequently at the bulwark of Resistance to Change. None of us can claim exemption from this human frailty. Growth depends upon change, yet it is resisted. If you set a goal to start your life anew, you must change your point of view.

Resistance to Change appears deeply rooted to hesitancy in using anything with which we are not familiar. Growth depends upon change and understanding. We oppose change while reveling in attempts to grow, all the while avoiding the basic principles of Physics, Mathematics, Inorganic and Organic Chemistry. These are powerful forces akin to logic, and logic akin to epidemiology follows the basics in science, not the other way around.

Consider the impressive concept of Dr. Nicholas Stravitis, St. Vincent Hospital, Cleveland, at the Annual Convention of the Ohio Association of Osteopathic Physicians and Surgeons, where he stated: ‘Disregard the search for the drug in overdose. All approaches for a diagnosis are the same; the vital signs will lead to the diagnosis that leads to the solution’.

This theory re-enforces Dr. Andrew Taylor Still’s thesis of thinking ‘from cause to effect and back again’. The body’s vital signs reflect the etiology as well as the corrective procedure; i.e., establishing the patient’s airway and controlling loss of blood obviously race for early correction where minutes, even seconds, clamor for top priority.

Cardiac dysfunction, blood chemistry, dishomeostasis and less important entities from the standpoint of time, require widening this concept to no greater than the level of the cell. Therefore, dishomeostasis, reduced to its lowest common denominator, becomes the key to pathology: the ubiquitous anion/cation. In this book, ‘anion’ is used interchangeably with ‘co-anion’, and ‘cation’ with ‘counter-ion’.

Inorganic electrolytes are prime suspects in pathology. Dimitri Mendelyeev succinctly reduced chaos to order with this statement: ‘Colloids under the control of the cation produce agglomeration, whereas colloids under the control of the anion produce dispersion’. It serves no purpose to search for the particular toxic substance, but rather race to identify total Cationic Electrolytes responsible for the pathology.

Pathology is associated with elevated cations. Essential cat-ionic surfactants (Na+, K+, Ca⁺⁺ and Mg⁺⁺) are seldom etiological except through cationic deficits, and those generally through ia-trogenicity. Identifying cationic surfactants is easily detected in urine samples via use of the Specific Conductance Meter.

In searching for the cause of a disruption of homeostasis involving a host of entities, including Thrombocythemia, Peripheral Vascular Disease, Intravascular Coagulation, Deep Venous Thrombosis, Pulmonary Emboli and many others, I am not searching for a specific abnormality, but rather for surpluses sufficient to disrupt the system.

The blood system, the digestive system, the brain and the central nervous system (with its sympathetic and parasympathetic energies ebbing and flowing) persists as long as life exists.

Physicians seek the departure from the normal. No greater or more frequent variation from the normal can be found than the deviation of electrolytes within human plasma. Plasma is frequently characterized as the most sophisticated solution in the universe. Plasma possesses such duality as remaining fluid (Thixotrophy) within a closed system (in vivo) yet able to close an opening (Dila-tancy), once blood is shed or an incision occurs.

Plasma constitutes a system that had to exist before life could exist. The medical profession has used the calculation of the Os-molarity Index as a tool to evaluate Isotonicity, generally regarded as 290 milliosmhos. While physiologically sound, this method is not far-reaching enough for our medical practice.

Specific Conductivity is highly effective in the accurate evaluation of Total Dissolved Solids within urine. This proves a quick and efficient method used to diagnose dishomeostasis. To date no one has successfully and accurately measured Total Dissolved Solids within shed blood.

The mono-, di-and tri-valent cations are the culprits and are seldom the essential Cationic Electrolytes earlier mentioned. Ecological cations are frequently the culprits, numbering in the hundreds and erroneously approved by the Federal Drug Administration as GRAS (Generally Regarded as Safe). Disregard the search for a specific toxin; rather, search for the presence of the Total Dissolved Solids affecting vital signs, which leads to the proper diagnosis and ultimately to a cure.

With current political stress on patient involvement, and with the help of a competent Generalist, such a medical practice has universal appeal.

It is a source of great comfort to isolate the etiological factors in Cardiovascular-Renal Disease, the leading cause of hospitalization and ultimate big-ticket and high tech procedures at the heart of today’s health crisis.

Using the indicated applied surfactant, renal calculi (kidney stones) can be reduced and passed within 5 hours without lithot-ripsy. Hemorrhoids and larger venous obstructions require a bit more time but generally not exceeding 4 to 5 days to asymptomatic conditions. It appears most post-operative Deep Venous Thrombosis and Pulmonary Emboli incidents could be eliminated.

The calculation of Specific Conductance provides early insight into the etiology at the level of the cell and indicates the proper regimen.

Chapter 3:

A NEW POINT OF VIEW

The three main areas of our focus will be:

• Endocrine Disorders

• Blood disorders relating to Diabetes Mellitus I and II

• Malfunction of the Cardiovascular Renal system

For a quarter of a century after its introduction in the late 1940’s, Cortisone’s excitingly effective use in the treatment of a variety of disorders gave great hope to many. Its efficacy was short-lived, however, and reports of Cushing’s Syndrome and unexplained deaths following its use began to appear.

Practitioners in every field hesitated to use pharmacological doses of Prednisone, Prednisolone, Triamcinalone and Butazoladin when it became known that these drugs produced grim complications. For years, Physicians have considered any dosage of synthetic Glucocorticoid potentially hazardous, electing to use them only as a last resort.

Then, in 1981, William McKinely Jefferies, MD, published his Safe Uses of Cortisone. Understanding the rationale of using physiological doses of Cortisone turned the management of disorders associated with Adrenal Insufficiency 180 degrees.

In the 1970’s, the World Health Organization was instrumental in a great change in the language describing Hyperglycemia. Gone are the terms ‘early’ or ‘late’ onset Diabetes, Brittle Diabetes, and Borderline Diabetes. In place of these general terms, more specific language clarified the confusion. Now, all diabetic cases are classified as Diabetes Mellitus Type I or II.

The change in the language and the introduction of divided doses of short-acting and long-acting Insulin brought a better understanding of the disease and a method to control Hyperglycemia.

A mentor at the University of California, San Francisco, himself a Diabetic from early adulthood, gave me understanding of Type I Diabetes, an entity controlled only by Insulin. He taught that control was best accomplished by administering divided doses of Insulin and long-acting Lente Insulin: more units of the former and less of the latter given in the morning to meet the needs of the 12 hours with great food intake, and the reverse for the second 12 hours of the day with, normally, less food intake.

Thus, the unit dosage of regular insulin is more in the morning and less in the evening. Reversal of the morning and evening insulin unit doses becomes an easy and effective system of support for a patient in need of insulin.

Type II Diabetes results from receptor inadequacies rather than from inadequate insulin supplies; therefore, tight control of glucose levels is the most effective treatment. With proper patient education, control of fluctuating blood glucose levels is placed where it belongs—in the hands of the patient.

More than 60% of the patients coming into my office with a prior diagnosis of Diabetes are out of control, many carrying elevated blood sugar levels 200mg/dcl greater than physiologic blood sugars.

Diabetic Gangrene, Intermittent Claudication and the prospect of extremity amputation are some of the reasons for seeking another Physician.

Cardiovascular-Renal Disease is responsible for 1.2 million deaths per annum. In 1968, when my personal activity was curtailed with acute symptoms of this disease, the outstanding Cardiologist in Cincinnati told me the profession needed more research when I pressed him for the etiology.

The Director of Research of one of the nation’s outstanding Cardiovascular Clinics, himself stricken with a heart attack, told reporters ‘I do not have the slightest idea why this occurred’. One wonders if ‘experts’ can exist in the absence of ‘expertise’! Today’s statistical approach to Cardiovascular-Renal Disease through numerous clinical trials is not always dependable because much of the data does not permit differentiation between cause and effect. And too, it invites erroneous inferences in situations where a high degree of correlation exists but where such agreement is purely coincidental.

Classical physiology and cardiology do not properly appraise heart disease. Read carefully:

The entire modus operandi of coagulation of blood as it is generally conceived has no remote similarity to the laws controlling coagulation in all natural systems. There are many cases on record where a person received a thorough medical examination (including an EKG) and was pronounced in excellent condition, only to die of a heart attack within hours!

This is untenable, and I believe these occurrences are due to the following reasons:

1. Lack of proper recognition of the vital role of Intravascular Coagulation in producing morbidity and death.

2. Insufficient recognition of the role of dissolved mineral salts in overloading the blood system and producing Intravascular Coagulation.

3. The inability of the kidneys to remove the high concentration of mineral salts, particularly in the presence of low water-volume intake.

Many facets of Cardiovascular-Renal Disease remain generally unknown or uncertain because their true relevance to a certain Natural Law has never been understood and accepted by the medical community.

In 1878, Hermann von Helmholtz, the father of Zeta Potential, established the mathematical basis for the physical chemistry covering the stability of liquid-solid systems, including milk, oil, emulsions, urine and blood. This mathematical theory applies to both suspensoids and colloids.

An extension of von Helmholtz’s findings has proved that his concept does work. In fact, it truly constitutes the natural Basic Law of Zeta Potential.

In 1628 when Harvey presented his Thesis entitled “Motion of the Heart and Blood in Animals”, he stated: ‘The blood therefore required to have motion, and indeed such a motion that it should return to the heart; for sent to the external parts of the body, far from its fountain, as Aristotle says, and without motion, it would become congealed’.

I am convinced that Harvey’s thesis is one of the most straightforward and perceptive pieces of technical writing in existence. This entire concept and expression is within the grasp of even the most modestly educated person.

Why does the medical profession take such a dim view of new scientific concepts—even (perhaps especially) those that arise from within its ranks?

Harvey knew that disease induced Coagulation of the blood. He states ‘ … tertian fever … renders the patient short winded … and indisposed to exertion because the vital principle is oppressed, and the blood forced into the lungs and rendered thick’.

Peer pressure was so strong that he wrote ‘what remains to be said is of a character so novel … that I not only fear injury to myself from the entry of a few, but I tremble lest I have mankind at large for my enemies … ‘. After three centuries, the same can be said today for those of us charting new territory.

When Jenner presented his findings concerning vaccinations and smallpox, the president of the Royal Society admonished that he ‘should be cautious and prudent … and ought not risk his reputation by presenting to the learned body anything that appeared so much at variance with established knowledge’.

Three centuries later the reticence to publish is smothered by the demand to publish; otherwise America’s scientists would not have access to parts of the $92 billion of grants annually available for research.

‘Publish or Perish’ has become an axiom.

Top scientists at some prestigious universities have quietly resigned with voluntary or court-fixed guilt; guilty of altering the data, manufacturing information with full knowledge the data is dishonest.

A former Surgeon General deplores the state of incompetence in physicians, and our failure to offer affordable, preventive and efficacious medical help for people to handle every day events of life.

People are angry and fearful about medical incompetence. Advancing years push many of our senior citizens, with waning health and little money, into the inevitable ambulance run to the Emergency Room, surgical ward, intensive care unit, eventually hurtling them to the Nursing Home.

They face a prolonged expensive decline of health. Meanwhile, they are prescribed and ingesting ‘hands full’ of drugs with side effects leading to either addiction or disability. Admittedly, we all have to go sometime! The years in our life give way to the prayer for life in our years.

SOMETHING HAS TO CHANGE!

A history of WW II teaches that people grew stronger, and survived longer when forced to fend for themselves while physicians were at the Front.

There are Specialists who save our lives. The point made here is that the ‘specialization’ division of medical labor is ultimately detrimental. The difficulty bridging the gaps between Medicine, Physics, Mathematics, Physiology, Chemistry, Psychology, and Sociology produces problems so great they are self-defeating.

The need for the Generalist is unmistakable. Specialization limits understanding of the subject and produces conflicts by failure to grow outside the area of expertise. This is sufficient to eliminate cooperation between the scientific disciplines.

The medical profession hides behind the ‘inevitability of side effects’ written by the Pharmaceutical industry, implying we need further study or more research. In my opinion, ‘side effects’ is the open admission that physicians and medical researchers do not understand Electrophoresis or colloidal control of particles via co-anions and counter-ions in a solution.

This appears to be a departure from the basic laws of the universe that Shulze and Hardy postulated a century ago (later supported by von Helmholtz) that dispersion of a colloid occurs secondary to anionic presence in the solution; and that the opposite occurs (coagulation from van der Waals Forces) when the anion is negated by the overriding presence of the cation.

Special skills in surgery and other technical areas deserve much praise. However, high tech medicine is losing ground to the prevention of disease and the return to the involvement of the patient in their medical treatment.

If Ronald Reagan had been the victim of a Coronary Infarction instead of a bullet in 1982, the history of the world would have been altered. No elected official can politically survive a cardiac event since the public is well aware of the probability of a dramatically shortened life span for the infarct victim. Given a choice, take the bullet every time!

Physicians attending heart attack victims are failing because of their lack of knowledge of cause—and—effect, and their inability to train the patient in prevention or self-involvement.

Self-involvement in matters of health becomes imperative, preferably with a competent Generalist, but if necessary, alone.

Chapter 4:

SELF RESPONSIBILITY

Recapture your medical regimen from the high-tech, big ticket procedures and turn to self help and preventive care before you are subconsciously programmed to believe in ‘better living through chemistry’.

SOCIOLOGY

Understanding resides in the Conscious Mind, later introduced into the Subconscious Mind wherein automation is perfected and most of life’s actions or reactions are handled.

What one believes or perceives before and after the age of reason generally is recorded within the Subconscious Mind. Rehearsal through repetition programs our response and a conditioned reflex is born. Without thought it performs—with or without veracity. The Subconscious Mind does not think or plan. It is not a goal-striving organ; it simply carries out orders as programmed, instructed or conditioned.

Thus, we begin learning the functions of the two brains and how we grow intellectually and physiologically. This constitutes a major social problem.

STAGE ONE: UNCONSCIOUS INCOMPETENCE

At this stage one does not know and is unaware. Moreover, one is unaware he/she does not know!, thus unaware of his/her incompetence.

STAGE TWO: CONSCIOUS INCOMPETENCE

The subject is still incompetent with the use of the disclosed information for want of rehearsal. Incompetence still exists, but the host is now conscious of the disclosure. No response to this information or skill is of value yet. This comes with rehearsal, leading to a conditioned response.

STAGE THREE: CONSCIOUS COMPETENCE

Conscious competence exists because the subject is aware of the disclosure or revelation and begins rehearsal of the new information out of free will to change or learn. Practice through mental or physical repetition causes some degree of competence, though conscious effort is necessary.

STAGE FOUR: UNCONSCIOUS COMPETENCE

Unconscious Competence becomes the final stage of learning, for herein lies the revelation or disclosure that is fixed within the Subconscious Mind; automation takes over repetition of the skill, resulting in competency.

Now the Conscious Mind frees itself of the necessity to remember. We instruct the Subconscious Mind. In reality, the Subconscious Mind is now acting as a servomechanism and with use/ practice, automation responds on cue.

An idea is planted. A motor skill is developed and performed without thought.

Conditioned reflexes respond on cue and the Conscious Mind is free to search for or ignore future revelations and disclosures. Of all the systems of the human body, the Brain and the Central Nervous System is the most difficult to change.

Stubborn, illogical and stupid are adjectives applied to the Central Nervous System and the Brain. Slow to read. Slow to grow through understanding. Each of us is programmed with many thoughts that are erroneous and illogical, put there by parents, siblings or peers who are misinformed or uninformed.

Now an explanation opens to why so many of us have illogical or incorrect opinions to which we cling. Unless we are exposed to the laws governing the mechanism of change through the stages of influence via change, we are adamant. We dig in and resist change.

WATCH THIS

The Innovator, usually one, has a revelation he perceives as truth. A great idea! The Innovator gains some early converts to his/ her idea and Stage II is born, the Early Adapters.

The Early Adapters come under the influence of the Innovator and a minority grows. They, in turn, influence a majority that becomes strong enough not to be denied.

The final step to change meets the traditionalist, the keeper of the status quo, the present leader, the Resistor to Change. He digs in and there follows a war of words, or deeds—war full blown.

The fight for survival is at hand. Traditionalism ridicules, bribes, and then goes to war. Traditionalism does not die; it has to be destroyed. Governments, nations and individuals face these forces enroute to change. Learning requires change. Learning produces pain or fear of it.

One cannot start life anew without a change in Point of View.

The new Point of View prevails in the Conscious Mind and is summarily pushed into the Subconscious Mind, then rehearsed to the Conditioned Reflex. New automatic response is born, nurtured, matured, never to be erased until the Conscious Mind decides to start anew.

The battle of change goes on as long as one grows. Growth cannot occur without a change in Point of View. Many, if not all, are adamantly resistant to change.

“I’m from Missouri—you gotta show me”. “That’s not the way I learned it”. “Been doing it this way all my life”. These are verbal expressions of a strong Resistance to Change factor. My father rode a horse from Manchester to Pineville, Kentucky circa 1907, and came home to tell my Mother the following story. ‘Alice, I saw the brightest light I ever saw in my life in that hotel room. A wire came down out of the ceiling, with a bulb at the end. They call it electricity. Funny thing. You could read a newspaper 10 feet away. No need to be close to the lamp. Matter of fact, there was a small sign near the switch on the wall that read ‘don’t strike a match, turn the switch’.

The observance of the electric light was so impressive he would have wired his home that week. He had to wait 37 years for the Tennessee Valley Authority to produce the hydroelectric generators, and the political courage to build it.

Millions had to change their point of view. Sociological change in Appalachia and the South will never be the same.

Sociology is full of struggles from which none but the brave, willing to suppress the ego, fully realize growth through change. They are truly responsible for society’s progress. Sociology, the child of Psychology and Psychiatry, can best be understood through Physical Chemistry (inorganic and organic), a small umbrella covering a great field of knowledge.

Chapter 5:

APPLYING SCIENTIFIC PRINCIPLES

General Chemistry is the child of the alchemist of another century. The masters of Physics have displayed genius in giving us an understanding of the elements of the earth, now unofficially numbering 109. Less than half a century ago, it was thought there were only 98 elements.

The elements, of which Oxygen, Hydrogen, Sodium, Potassium, Chlorine and the Sulfates are but a few of the total, make up all earthly matter.

Of these elements, 19 are labeled the most precious elements in that they maintain life and without which life could not exist. Schulze, Hardy, Mendelyeev, von Helmholtz, Krogh, Planck, Bernard, Bohr, Riddick, Knisley and hundreds more have contributed to our knowledge.

Through their genius we (now nearing the 21st Century) now have the knowledge to maintain healthful circulatory systems void of the clotting, clumping, agglutination, precipitation, ‘salting out’—only a few of the names describing the cause of malfunction of the Cardiovascular-Renal System.

What has been overlooked? The writings of the above mentioned scientists have given us the knowledge to prevent and reverse Cardiovascular-Renal pathology.

Thrombocythemia (frequently termed Intravascular Coagulation), is a constant in all circulatory disorders.

Physicists Stephen Hawking, Murray Gell-Mann, Hans Selye and Israel Neeman have all chronicled their explanation of Particle Control by Electrons.

All mass is aggregates of particles. Particles are divided composites of mass.

Before Mendelyeev, much of Chemistry was a jumble of factors. When he placed the then-known elements in proper rows and columns he brought a high degree of order out of chaos.

Similarly, an orderly and proper view of Zeta Potential brings order to the vast present knowledge of practicable and theoretical colloid stability. Above all, it stresses the real importance of di-, tri-and polyvalent ions and their overwhelming control over Coagulation when associated with the cation, or their control of Dispersion when associated with the anion.

These concepts were underscored in 1883 by Shulze and Hardy. About this time, Hermann von Helmholtz was developing the basic concept of Zeta Potential, which later rationalized the experimental evidence of Schulze and Hardy.

It is imperative to establish these credits, because whatever contribution is made in these pages rightly goes to those who have preceded this writing. No intent is made to establish originality, implied or actual. I count my good fortune, and to a large extent, good health and longevity, to these scientists.

Their clarity of reason, scientific acumen, and the availability of their writings (despite the difficulty uncovering their works) are the basis for our work in this area during the past 30 years.

Efforts to uncover their works required years of searching, and longer, years to decipher their genius. It took courage to put these principles into practice on my own failing health.

Later I gained courage to apply these principles to my patients, now numbering approximately 11,000. They have been the recipients of efficacious knowledge clearly responsible for their return to active, healthy lives. More than a few of us are in the final quarter of our century of fulfilling lives.

GOLDEN YEARS, indeed!

This book is no wild claim or intent to blow my own horn. Rather, like Dizzy Dean, who characteristically proclaimed to the

sports world: ‘Me and brother Paul are gonna win 23 games apiece for the Gas House Gang of St. Louis this year; it ain’t bragging if we do it’. And they did.

Chapter 6:

CHEMISTRY, MATH AND PHYSICS

More than 39 diseases, secondary to particle aggregation, have been controlled by Electrophoresis (Anionic Surfactant Therapy) using the fundamental laws of Electromagnetic Force, or EMF.

Elsewhere we will discuss the constant and predictable behavior of particles (also called colloids or suspensoids) in the size range of 10 microns down to 100 angstroms while under the influence of the anion of the bulk stress of the slurry in which the particle moves.

No doubt, you have had some exposure to magnetism. Usually introduction to this natural phenomenon is by age twelve, in some early school classroom, involving the horseshoe-shaped piece of metal displaying a strange phenomenon. The end of the fork repels the metal object, and the other end attracts the metal object. You recognized early this strange, invisible force and probably recall it as an example of magnetism.

Modern Physics proclaims the natural law of colloidal (particle) behavior influenced by the (+) positive charge and the (-) negative charge as being representative of a fundamental and irrefutable law of the universe: co-ions repel; counter-ions attract.

Every particle of mass falls under the rule of the law now referred to as Electromagnetic Force (EMF) or Zeta Potential.

As you recall, revelation of new information is easier to comprehend if you can observe it. But what do we do about things we cannot see or observe, such as headaches and/or backaches? Surgery and medication are usually ineffective. Electrons are not observable with the naked eye but instruments detect their presence.

Electrons are measured in millivolts Zeta Potential, and are a subdivision of ohms. The reciprocal of ohms x 1,000,000 equal Zeta Potential in millivolts. Recent language measures this in microsiemens.

It has been my good fortune to hold a number of seminars in my office over the past several years. Attendees have been from some of America’s most prestigious universities, and have included Internists, Surgeons, Oncologists, MD’s and D.O.’s, Pharmacists, Dentists, DC’s, Generalists, Radiologists and Registered Nurses, all professionals qualified by reason or by training and licensed by examination to practice their craft.

This is not an attempt to denigrate or show disrespect, only to show the state-of-the-art that the graduates of these top-flight schools project. Moreover, these professionals out number me considerably.

While I lead the Seminars, I am certain I learn as much from them as they learn from me. Remember: my training was no better or no worse than theirs, though I have been licensed by examination in Missouri and Ohio, and by reciprocity in Kentucky.

In the final analysis, opportunity prevailed and validated course content. Medical professionals generally agree our knowledge of Inorganic and Organic Chemistry, nutrition and personal health information is woefully lacking. Some even (in a back-handed swipe) imply it is not their need to learn Prevention.

Most of us are painfully aware these subjects were not taught when we matriculated, and an inordinately high number of professionals move into the field of specialization.

Despite the fact that Osteopathic emphasis is on developing skills useful in supporting Dr. Andrew Taylor Still’s edict ‘The Rule of the Artery Is Supreme’, I have discovered few of us could name the 19 inorganic minerals considered endogenous to normal plasma electrolytes.

Widening ‘The Rule of the Artery’ to include Electromagnetic Force, Drs. Still and von Helmholtz were contemporaries. Poor communication precluded their mutual support of Dilatancy and Thixotrophy. It would be a century before those two concepts would be wedded into full comprehension of prevention, treatment and reversal of Cardiovascular-Renal Disease and supply a working model for solution of circulatory problems.

The Seminars we conduct for the Golden Years Society, Inc., have convinced me the weakness is that of philosophy (or lack of it), and definitely not a lack of information laid down by scientists a century ago, but the failure of Medical Schools to apply this knowledge in their teaching.

Duncan J. Shaw, in the 3rd Edition Introduction to Colloid and Surface Chemistry states: colloid science is very much an interdisciplinary subject, albeit with certain areas of Physics and Chemistry most prominent.

Owing to the complexity of most colloid systems, the subject often cannot be treated readily with the exactness that tends to be associated with much of these major subject areas.

It is probably a combination of this lack of precision and its interdisciplinary nature (rather than lack of importance) that has been responsible in the past for an unjustifiable tendency to neglect Colloidal Science during undergraduate academic training.

Colloid chemistry, particle behavior under the influence of the essential and trace minerals, represents the nucleus of an effective regimen in controlling malfunction of the Cardiovascular system. In the absence of understanding Colloidal Control Through Zeta Potential, millions are deprived of a safe, efficacious understanding of why we succumb to diseases.

Prevention is relegated to a common expression defining our attitude about weather; to wit everybody talks about the weather but no one does anything about it.

Everyone has succumbed to the belief that nothing can be done about prevention of Cardiovascular malfunction, not withstanding the millions that are now on cholesterol and triglyceride-lowering medications, and their disappointment with continued pathology.

Let the alert lead

Let common sense prevail

Let each of us become aware that Cardiovascular events are preventable, treatable AND reversible. Let us understand we must become a part of our own health, or decline.

No Physician can take care of you without your personal involvement. Your quality of health care is proportional to this involvement. Physiological Bankruptcy runs parallel to fiscal bankruptcy. Self-involvement in recovery from either is mandatory.

No Endocrinologist can care for your Diabetes except through knowledge implanted within your brain. Abdication of your financial decisions to your banker or others is equally catastrophic for obvious reasons. Become involved or become an invalid before your time.

Earlier recognizing the umbrella of Physics and lesser but essential disciplines embracing the compendium of organized science, it appears out of reach for one human mind to grasp it all. Murray Gell-Mann, the noted Physicist, said: ‘It is nearly impossible for the human mind to bridge the gap between these differences’.

Could THIS be the driving force toward Specialization within medicine? Could THIS be the etiology of tunnel vision: that Specialists represent the epitome of knowledge and he/she therefore becomes the keeper of that knowledge and is by edict the sole distributor.

One of America’s top basketball coaches in the late 1980’s clearly reduced his team’s chances for success in the NCAA National Championship to the lowest common denominator.

He said ‘Do what has brought us here. We’re going to watch game films for fundamentals; the team which makes the fewest mistakes wins’.

BINGO!

Obviously handling the repeated motions, moves, reflexes and patterns that brought them to the NCAA Final Four had to be recognized with no time for introduction of something new. No time to change.

He wrote your life and mine with those words. Make fewer mistakes if you want to stay in ‘the game of life’ into your Golden Years. Success is obvious if your team is in the Final Four. His wisdom was overwhelmingly basic.

Physicians are in an unenviable position. The final common pathway to oblivion is not heartwarming. The screaming ambulance run, an automated open door into an Emergency Room, abdication of the emergency to an unknown Physician, surgical assault and subsequent exit of that theater into Intensive Care, then, hopefully, home (either the nursing home or the funeral home), is not a pleasant scenario to contemplate.

PROTECTIVE MAINTENANCE PREVENTIVE MAINTENANCE

America’s industries understand Colloidal Chemistry. America’s Physicians do not.

Chapter 7:

ADSORPTION AND DESORPTION

Surface Chemistry easily translates into Colloidal or Surfactant Chemistry. A particle in the size range of 10 microns to 200 angstroms preferentially adsorb the Anion to its periphery. From distilled or tap water the OH^-ion from HOH supplies this ubiquitous ion. Hence, HO is labeled the Universal Solvent.

It is the energy from the OH^-radical that is responsible for the mutual dispersion of these small particles (colloids) throughout the universe. Being adhered to the surface of the particle, the energy of one particle (either anionic or cationic charged) behaves with respect to its neighbor, similarly charged, producing mutual repulsion.

Technically these co-ions (similarly charged) support a universal law of mutual repulsion. Schulze and Hardy, von Helmholtz, Riddick, Melvin Knisely and a host of others have written on the basics of Colloidal Chemistry and Colloidal Intravascular Dispersion.

Using Minusil as a particle on which a variety of anionic surfactants will adsorb, Thomas Riddick has chronicled the behavior of colloids while under the influence of the anion.

Distance between suspended colloids is measured in millivolts and is described as Electrophoretic Mobility, or Zeta Potential. Riddick has reported the following in support of his viewing of the colloid at zero Zeta Potential, wherein massive agglomeration is obvious, compared to a dispersed solution at-22mv. See Exhibit 1 (Colloidal Systems).

and suspensoids (blood formed elements) occurs from the onset of agglomeration at approximately-15 to maximum dispersion at-100 . In other

A A ^J mv A mv

words, to support dispersion of plasma particles requires maintenance of electrolytes of anionic source to insure Dilatancy and Thixotrophy (Coagulation and Dispersion).

Dispersion is the desirable; its antithesis, agglomeration, is the basis of Intravascular Coagulation, viewed to be the constant in Cardiovascular-Renal pathology.

Co-ions preferentially adsorb to the colloid. With serial and geometric dilution, the anion can be desorbed. The desorption curve demonstrates why an anionically dispersed system CANNOT be diluted without materially lowering the Zeta Potential, which leads to agglomeration at approximately-15 The converse of adsorption is desorption. The anion is the controlling energy responsible for cellular excitement. It is imperative that any attempt to control electrolytes of a plasma slurry without a thorough understanding of these electrolytes invites disaster and insures violation of an ancient edict: above all, do no harm. See Exhibit 3 (Desorption Curves).

To establish understanding of anionic control of colloids on behalf of desired dispersion in health, let us digress to form a working knowledge of the essential and trace minerals of human plasma. See Exhibit 4 (Essential Electrolytes in Human Plasma).

When matter is heated to a very high temperature (>5000 C), collisions between particles are so violent that electrons are knocked away from atoms. Such a state of matter, composed of electrons and positive ions, is called a plasma. The study of plasma is called Magnetohydrodynamics.

Albritton and others have given us an understanding of plasma electrolytes and their overall colloidal control. It is generally understood that these plasma electrolytes are present in the normal healthy individual at approximately 9 grams per liter of plasma.

• Consider that one pound of minerals weigh approximately 454 grams; that’s a very small amount, approximately a tablespoon

• These 9 grams are easily divided into only two categories: Elements or Minerals, Positive or Negative charges; co-anions or counter-ions.

• Four of them (Essentials) are Cationic and are positively charged.

• Four of them (Essentials) are Anionic and negatively charged.

Eleven of them are considered Trace Minerals, 8 of which are Cationic and 3 of which are Anionic. Note the total is 9083 mg./ Liter or 9,000 mg./Liter of essential minerals. Grams equate to 9 grams of Essential Electrolytes. See Exhibits 1, 4 and 5.

Medical professionals will recall the Halogen sisters (Fluorine, Bromine, Iodine & Chlorine). Chlorine is the primary anion, representing 3700 mg./L of the total co-anions at 5507.56 essential and trace minerals. Chlorine will become the most maligned anion within the uninformed or misinformed during the 1980’s.

Chlorine is second to none in importance to modern civilization given her ubiquitous presence in plasma and other solutions essential to life, not the least of which is Chlorinated H2O fit to drink, and the supply of Cl^-ions in a multi billion dollar soap industry and other particle dispersion needs of a polluted earth.

If you have the urge to point the finger of scorn at the Halogen sisters, reserve it for adulterous Fluorine whose very nature is her willingness to counter-ionically hook up with any mono-valentcation or amino acid. Such union with Fluorine supplies the lineage to the tri-halo Methanes and other compounds thought to be carcinogenic.

It is well documented that in excess of 3—4 ppm of Fluorine will combine with the Calcium of teeth, producing the appearance of abrasions called Fluorosis. Dentists agree Fluorine will in

hibit cavities; the trick is to prevent Fluorosis via toxic excess (generally above 4 ).

This leads to a succinct definition of toxicity or ‘side effects’ of a drug.

It is simply TOO MUCH.

It behooves all Physicians to know the therapeutic, toxic and lethal dose of all chemicals ingested. One cannot easily determine toxicity without knowing the norm; hence, chemistry is a mandatory subject to master if one uses drugs.

It is not enough to hide behind the Physicians Desk Reference disclaimers that fill pages if not volumes. Patients are asking ‘Is this drug in my best interest?’. This is as it should be.

Our advice is succinct:

Become involved in your health decision. Ask for explanation as to how any drug prescribed for your illness works. If you don’t get a meaningful specific, or if you get some wandering generality seek another Physician and do it instantly. Any Physician who cannot or will not explain or assist in your education or health involvement should be shunned like exposure to AIDS.

Why do Physicians think the way they do? In The Origin of Consciousness in the Breakdown of the Bicameral Mind, Julian Jaynes provides an easy explanation of the broad definition of medical practice subdivided into two areas of thought.

1. The Art of Medicine

2. The Science of Medicine

A Physician whose approach to medicine is via art (right brain control) functions from experience only, or via summations of conditioned reflexes, and observations controlling his practices.

Without left brain function (control of thought related to all scientific knowledge under the umbrella of Physics and other scientific areas), the right brain Physician does not embrace the total practice of the compendium of science. Right brain limitations are fraught with subjective opinions or Rorschach interpretation. Left brain function is dictated by the objectivity of science and fundamental laws of the Universe. Such fundamental laws, governed by the Science of Medicine, precludes the Art of Medicine and moves the competent Physician into wide lens viewing of all medical matters. It is not easy but demands the effort if we indeed do no harm.

Code of Ethics #2 of the American Osteopathic Association, and Code of Ethics #5 of the American Medical Association reads: All Physicians shall study, apply and advance scientific knowledge to maintain ethics.

I know one state (there may be others) that has resisted requirements for licensure via continuing medical education.

One School of Medicine’s modalities are admonished at the State Charter level issuing the license to him/her to ‘go forth and improve the present system of medicine, surgery, midwifery, and place the same on a more rational and scientific basis’. That School of Medicine confers the Doctorate of Osteopathy, or D.O. degree. Osteopathic Manipulation plays a specific, unique role in maintaining homeostasis in pursuit of the ‘Rule of the Artery is Supreme’, now expanded for some of us to include blood colloidal chemistry through Zeta Potential.

Chapter 8:

THE ALKALINE RESERVE

The body performs at a pH of 7.35 with the range as wide as 6.8 to 9.0. pH is controlled by the Alkaline Reserve formula shown below.

Obviously if you are to be of assistance through choices of foods and drinks, you need to be aware how relative alkalinity and acidity is maintained. Therefore, in our office we use a pH tape that can be deposited for a brief second in saliva beneath the tongue or in a sample of urine recently drawn. The pH then is matched by a color sample ranging from a pH of 5.0 to a pH of 9.0.

The body is constantly being challenged by stresses from without by way of food and drink, relatively so with dehydration and or hydration, and what one eats and drinks when the Total Dissolved Solids of human plasma are measured and well understood.

The Parietal cells of the stomach represent a basic source of alkalinity or acidity with production of the substance called Hydrochloric Acid.

The pH ‘dipstick’ is an excellent source of dependability in measuring alkalinity, acidity, and any reading between the aforementioned extreme range.

MILLIOSMHOS OF HUMAN PLASMA

To measure homeostasis by another approach, Extracellular Fluid (ECF) and Intraplasma Fluid (IPF) cooperate with the consistency of man and wife in a happy home. They share and share alike the workload and the joys.

Most Physicians are aware of the use of 3 elements in calculating homeostasis or Isotonicity of electrolytes in the plasma. The following formula explains the mathematics to arrive at Isotonicity or a deviate.

When working with any unknown colloid system of importance, you should always investigate the relationship of Zeta Potential and pH. Inorganic compounds that are highly insoluble in acids and alkalines will be affected by pH. Nearly all Zeta Potential-pH curves ‘salt out’ (precipitate) at the extremes: pH 1-3 and pH 12-14.

Some colloids, inorganic or organic, dissolve at extremely low or high pH. Therefore, it is important to keep pH on the alkaline side for discrete dispersion of plasma formed elements; acidosis and ketosis secondary to hyperglycemia promotes slowed plasma flow; antegrade flow is important.

Stasis is an unwanted and unacceptable pattern of Thixotrophy. Retrograde flow, like peripheral resistance, at arteriole-venule anastomosis sites produces hypertension followed by venous valvular damage. Surgeons like to call this valvular prolapse and perform invasive surgery for relief.

In an early 1980’s case, we saw an employee who was advised to undergo valve replacement; she received competent valvular function following Anionic Surfactant Therapy.

Albumin and other plasma serum proteins (and their electrolytes) are the most important of all systems.

One unit change of pH in human blood can cause a change of

-8 . At either dispersion or agglomeration threshold, this is highly significant.

Returning to the Osmolarity Index, to itemize the numbers in the formula let’s choose a Sodium mEq in a range of 137 to 152 mEq, plus Glucose in mg/dcl-H by 19, plus BUN + by 2.5.

In epidemiological studies using thousands of people, homeo-stasis has been pinpointed at approximately 290 milliosmhos. Should that number reach higher than 290 this would clearly be translated into Hypertonicity, which is another way of saying elevated cationic surfactants.

Accompanying this numerical reading would be a high propensity toward Congestive Heart Failure, Tibial or Proximal pitting Edema and Cardiovascular incidents.

Thus, it follows that if the reading is below 290 milliosmhos, the result is Hypotonicity, and cationic electrolytes (generally the essential plasma electrolytes of Sodium, Potassium, Calcium and Magnesium) are depleted.

The end result produces cardiac irregularities ranging all the way from heart blockage to cardiac arrest to the aforementioned PVC’s, Edema, General Malaise, Claudication and Insomnia.

Teleological medicine (everything happens for a reason) is a thread that runs so true throughout the Osteopathic concept. Keep in mind the major tenant, The Rule of the Artery is Supreme. This is well understood by graduates of the Osteopathic School of Medicine.

Dr. Andrew Taylor Still correctly assumed that of the Para-sympathetic sections of the spinal cord, the Cranial-Sacral segments control electrolytes by way of inhibition. In other words, a Cranial or Sacral Osteopathic Lesion could affect the movements of cationic electrolytes, causing the inhibition of the essential cations. Later, a further and more detailed account of the essential cationic surfactants in plasma will be re-addressed.

Conversely, should there be an excess of other cationic surfactants—not necessarily the aforementioned essential quartet—we now need to turn attention to other surfactants that gain their way into blood plasma by food, drink, drugs and the ecology.

Herein lies the importance of Specific Conductance. We consider this to be an important calculation for use by a Generalist to properly evaluate the internal constants responsible for homeosta-sis and the converse, dishomeostasis.

Hermann von Helmholtz and Dr. Andrew Taylor Still were contemporaries who lived a continent apart in the closing decades of the 19th Century. They may be forgiven for not knowing of each other’s approach in support of homeostasis.

Future physicists and chemists of America’s young universities came under the tutelage of von Helmholtz. It was he who showed future scientists and physicians (who would read and heed) that the energy associated with the beginning of life and sustaining life had to be in existence before life would begin.

The ‘biological terrain’ or the internal components of blood (the formed elements, liquid volume, and 19 essential electrolytes) had to prevail before a fetus could begin its treacherous growth pattern throughout the maternal life, within a slurry that contained a balance between ECF and IVF.

The question now is how much this same new form of life will be wronged in the early childhood days and throughout the stages to adulthood and finally to the geriatric patient.

Hermann von Helmholtz and an associate, Smolukowski, have postulated the degree of fluidity of the suspensoids (the formed elements) and colloids under the Law of Electrophoresis, Electro-phoretic Mobility or Zeta Potential.

We can easily calculate Specific Conductance from a urine sample that is then converted to Zeta Potential. This formula (discussed in detail later) will give you a wider, more inclusive study of the electrolytes that produce Hypertonicity.

From the von Helmholtz-Smolukowski Table in Exhibit 6, you can see the numerical point of Agglomeration, Precipitation, Intravascular Coagulation, Thrombocythemia, all of which are etio-logical to such ominous diagnoses as Deep Venous Thrombosis,

Pulmonary Emboli and Cardiovascular-Renal Disease, as well as a number of other adjectives that would indicate interruption of the antegrade flow of the plasma and its contents.

von Helmholtz broadened his statements that cationic electrolytes, based upon their valence, become powerful etiological events in the production of Thrombocythemia and Intravascular Coagulation.

We take a wide-angle approach involving the damage done by high cationic surfactants from the ecology, food, drinks and medicines.

Without measuring these additional cationic surfactants that are such a part of the etiology of clot formation, we are sometimes likely to err and not understand how the trace cationic surfactants (Mercury, Aluminum, Copper, Tin and Zinc, to name a few) can produce a hypertonic solution higher than the reading when using only Sodium, Glucose and BUN in the above-referenced formula.

Once you calculate the Specific Conductivity, you have a reasonably accurate way of reducing these extraneous cationic electrolytes to the gravimetric equivalency of Sodium, and you can see an often-overlooked etiological factor in cardiovascular disease.

Chapter 9:

OUR REGIMEN

Some examples of systems that are colloidal in at least some respect are outlined below, and represent knowledge on the forefront of the world’s industrial advancement. Modern technical growth is superseded by understanding and controlling colloids. Examples of colloidal systems are listed below:

Aerosols	Pesticides
Pharmaceuticals	Fabrics
Inks, Paint & Dyes	Foodstuffs
Paper	Cosmetics
Foam & Emulsions	Cement
Plastics	Soil
Rubber

The investigation and classification of disperse systems began in the second half of the 19^th Century and has continued to evolve in these final few years entering the 21^st Century.

During the past 60 years, the study of these systems has been enhanced by the development of the Centrifuge, x-ray analysis and electron microscope, and more recently by high-tech computerized equipment capable of very precise measurements and documentation. The results of this research have been tremendously important in pure chemistry, industry, medicine and many other fields.

The primary focus of our discussion, however, is on the application of the principles of colloidal behavior to human blood, specifically to promote dispersion of the formed elements within the plasma slurry in achieving and maintaining optimum vascular function. See Exhibit 7 (Human Blood).

Colloids, which are included in the general term ‘disperse systems’, are extremely complex suspensions that may consist of many different particles in a liquid medium. They are highly dynamic, being subject to simultaneous gravitational and electrical forces, as well as to the effects of thermal agitation and to van der Waals Forces that apply specifically to colloids.

Also at work within the system are potentials, currents, pressures and forces acting upon the various interfaces such as the macroscopic interfaces that the solution shares with the air interfaces between the colloidal particles and the solution. These interactive forces are constantly changing the measurable qualities of the system until a state of equilibrium is reached.

An understanding of Zeta Potential, the force that maintains the discreteness of particles in a colloidal system, brings order to the study of practical and theoretical colloidal behavior.

The theory of Electrophoresis was developed by von Helmholtz in 1879, later broadened by Smolukowski in 1903, established the relationship between the electrokinetic potential of a colloid and its charge, referred to as Zeta Potential.

The control of Zeta Potential through anionic surfactants provides the means to establish a thoroughly dispersed, stable system.

As we alternate between simple man-made inorganic systems and sophisticated organic natural systems, we find the basic principles apply to both.

The smallest particle of an element is the atom, which is comprised of the electron, having a negative charge, and the proton, having a positive charge; the former being incapable of further division, while the latter is comprised of several known sub-atomic particles.

The term colloid can also be used to describe a particle in the size range of 10 Angstroms to 10 Microns. Colloidal particles may be aggregates of atoms or small molecules, or consist of a single very large molecule. In any event, they have an extremely large surface area for their mass, and they may carry dozens or even thousands of electrical charges.

Colloids in solution are subject to positive and/or negative charges through adsorption of ions. Colloids having a similar charge repel each other, and colloids having opposite charges attract each other.

The tendency of similarly charged colloids to repel each other or to remain discrete is referred to as Dispersion. The measured distance between the forces is expressed in millivolts (mv). This is Zeta Potential, a measure of the net electrical potential carried by a colloid.

Substantially, all colloids adsorb negative charges when suspended in water, in low ionic concentration, with a pH range of 5 to 10. They become electronegative. The negative charge of the ion determines basic colloidal Electrophoretic Mobility or discreteness.

Electrophoretic Mobility is influenced by the ionic concentration and pH of the system as well as the valence of the ion. In a system having low ionic concentration and a pH range of 5 to 10, the Zeta Potential will generally range from about-14 to-30mv. Zeta Potential values of less than-14mv usually represent the onset of agglomeration.

Ionic concentration results from the introduction of one or more elements into the system, producing an electrolyte solution. Inorganic elements hydrolyze in solution to dissociation, liberating a radical.

The hydrolysis of inorganic compounds into elemental components releases energy from the compound in the form of charged ions.

The resulting electronegative element is called an anion. The electropositive element of a dissociated molecule is called a cation, and sometimes referred to as a ‘free radical’.

Ions having similar charges repel each other, and ions having opposite charges attract each other.

The strength of the ionic concentration is measured by its conduction of an electric current called Specific Conductance. The term micromho is generally employed in expressing this conductivity; mho being the reciprocal of ohm, a unit of electrical resistance, times one million (1 one-millionth of an ohm).

Specific Conductance can be roughly converted to the gravimetric equivalent of Sodium by dividing by two. For example, a solution of NaCl produces a Specific Conductance of approximately 50,000 micromhos containing 25,000 ppm equivalent of NaCl.

When the concentration of an anionic electrolyte in a dilute colloid system is progressively increased, its Zeta Potential becomes more electronegative until it reaches a plateau; then reverses, and the colloid is eventually ‘salted out’. ‘Salting out’ refers to the agglomerating or flocculating effect of a high reagent concentration in a system.

Generally, electropositive colloids have achieved this state only through an applied cationic electrolyte or polyelectrolyte. When these electropositive systems are serially and geometrically diluted, the colloid desorbs and becomes electronegative again. See Exhibit 2 (Serial and Geometric Dilution).

The pH of a solution refers to the Hydrogen ions available for exchange, and is used to indicate the acid or basic quality of a solution. pH values range from 0 (pure acid) to 14 (pure alkaline) with 7 being neutral.

The valence of the ion can have a dramatic effect on Electro-phoretic Mobility, amplifying the Zeta Potential of the colloid in varying degrees. According to the Schulze-Hardy rule, di-valent cations are approximately 20 to 80 times as effective as monovalent cations in the agglomeration of electronegative colloids, and tri-valent cations are 10 to 100 times more effective in agglomeration of electronegative colloids.

All the particles in a system are involved in a continuous bombardment of each other, each collision producing a change in the direction of motion and a change in velocity. There are billions of these collisions per second, producing a random, zigzag path for each molecule.

This mechanical activity, called Brownian Motion, is connected with thermal activity to produce diffusion of the particles throughout the solution. Cigarette smoke in dilute concentrations is perhaps the most dramatic of all Brownian Motion examples, or examples of discretion.

A colloid particle suspended in water will adsorb a negative ion at its outer surface. An over simplified explanation for this is that there are more OH ions and that they fit better into the lattice structure of the colloid than the H+ ion, the latter being larger than the negative ion.

The negative surface of the colloid then attracts a surrounding layer of positive ions, which may come from the bulk of the suspending liquid or from the surface of the colloid itself. These counterions are drawn to the colloid by electrostatic attraction.

This charged system—the surface of the colloid and the neutralizing counterions—is called the Double Layer.

If the negative charge is large, some counterions will be so strongly attracted that they will stick to the surface of the colloid as a firmly-attached compact layer known as the Stern Layer.

This Stern Layer partially neutralizes the charge and electrostatic attraction of the colloid so that the remaining counterions can be further away, while being kept in the vicinity of the colloid. They form the so-called diffuse part of the Double Layer.

We will now outline combining the principles of Zeta Potential with colloidal science.

Chapter 10:

COLLOIDAL CONTROL

The basic purpose of the Law of Zeta Potential is the maintenance of fluidity in the aqueous system of plant and animal life.

Knisely, Bloch and associates at the University of South Carolina demonstrated that Intravascular Coagulation could readily be seen in the venules and arterioles of the sclera and/or conjunctiva of the human eye, and that a high degree of fluidity of the blood (without clumping of the formed elements) was characteristic of good health.

Conversely, a high degree of coagulation was inevitably associated with morbidity and death.

Cardiovascular-Renal Disease is caused by the kidneys becoming gradually debilitated and finally overwhelmed. The formed elements of the blood are gradually coagulated and ‘salted out’ in accordance with the laws of Zeta Potential.

The causes of Cardiovascular-Renal Disease are not difficult to understand provided you clearly see the whole picture. This requires some knowledge of Physical Chemistry, more particularly, it requires knowledge of Zeta Potential, which controls the stability of liquid-solid systems.

For instance, whether a handful of clay added to a half-liter of distilled water containing mineral salts will form an adhesive mass or disperse into billions of tiny particles, each remaining separate and discrete, depends almost entirely upon the Zeta Potential of the system.

You can apply an anionic surfactant (electrolyte) and bring the system to maximum dispersion. This law of physical chemistry is just as absolute and unyielding as the Law of Gravity. However, Newton’s law is observable even by a child.

The Law of Zeta Potential becomes self-evident only if we know where to look, how to look and what to look for. Further, in appraising Cardiovascular-Renal Disease it is mandatory to have a working knowledge of a chemical test based upon Specific Conductance.

It is the simplest of all tests for quantitatively evaluating the concentration of dissociated mineral salts in solution. Depending upon the number of ions available, and the resulting flow of current, it is possible to calculate the Specific Conductance of a given solution with its concentration of dissolved mineral salts.

The principles of Zeta Potential, once clearly understood by a Physician, should be effectively incorporated into a patient education program that places a clear emphasis on self-reliance and individual responsibility for maintaining good health.

This should be the ultimate goal of every Physician:

Make available to every patient the knowledge and skills necessary to achieve optimum health and longevity.

If you are a patient of the McDaniel Medical Clinic you are familiar with the daily urinalysis reported to you as either ‘Urine Count’ or ‘Total Dissolved Solids (TDS) Count’.

Over the years, many patients have inquired about purchasing one of these instruments for home use. They are valuable in the analysis of good health, and they are relatively inexpensive, approximately $350—$400 .

The Zeta Potential is the potential at the surface separating the immobile part of the Double Layer from the diffuse part, or the Net Potential. This will be discussed in Chapter 11.

As detailed in the previous chapter, Zeta Potential values less than-14 usually represent the onset of agglomeration. A plateau region, marking the threshold of either agglomeration or dispersion, exists from about-14 to-30mv. Values more electronegative than-30 generally represents sufficient mutual repulsion to result in stability.

When a system contains cations and anions of varying valences and electrolytes of varying concentrations, the possibilities for change in Zeta Potential are limitless.

Therefore, it is necessary to have some mechanism to maintain the complete discreteness of each colloid with no agglomeration to produce stability of the system. This stability can be achieved by several means.

• Adsorption of an ion on the colloid to create strong mutual repulsion.

• Adsorption of a strongly-hydrated hydrophilic protective colloid, such as gelatin, on a larger hydrophilic colloid. In this case, the affinity for water exceeds the mutual attraction of adjacent particles.

• Adsorption of a non-ionic polymer of sufficient chain length to create Steric Hindrance to prevent two particles coming close enough to join. This method is widely employed for emulsions.

A highly effective method of providing anions is through agents called surfactants. These agents act on the intermolecular forces surrounding the surface colloids to alter the Zeta Potential.

There are four classifications of Surfactants:

Co-Ionic Surfactants Counter-Ionic Surfactants

Non-ionic Surfactants Amphoteric Surfactants

Electrolyte solutions that produce the desired Ions serve as surfactants. The ions of both anionic and cationic electrolytes may carry from one to four charges and are accordingly designated mono, di-, tri-or polyvalent type electrolytes.

When the electrolytes are negatively charged, they are written as 1:1, 1:2, 1:3, or 1:4 to indicate the ratio and their respective ionic strength relating to successive increase in Zeta Potential and degree of dispersionary effect on the colloid.

ANIONIC ELECTROLYTES

1:1 Potassium Chloride	KCl
1:2 Potassium Sulfate	k2SO4
1: 3 Potassium Citrate	^C^^O
1:4 Tetrasodium Pyrophosphate	^Na4^P2^O7

When the electrolytes are positively charged, they are written as 1:1, 2:1, 3:1 or 4:1 to indicate the ratio and their respective ionic strength relating to successive decrease in Zeta Potential, which allows van der Waals Forces to come into play, resulting in agglomeration.

CATIONIC ELECTROLYTES

1:1	Sodium Chloride	NaCl
2:1	Calcium Chloride	CaCl2
3:1	Aluminum Sulfate	AlCl3²
4:1	Polyvalent Cations	AlCl3²

Natural short-range forces of attraction called van der Waals Forces become evident at Zeta Potential values below-15 to effect agglomeration in the absence of anionic charges on adjacent colloids.

At Zeta Potential values from-15 to-100mv, the mutual repulsion of colloids in dilute suspensions generally keep each particle sufficiently apart so that the van der Waals Forces cannot become effective. The relative ionic strengths of electrolytes can be calculated mathematically.

AGGLOMERATION OF COLLOIDS (IONIC STRENGTH)

AlCl3 = 1 x 3² + 3 x 1² = 12 /2 = 6

CaCl2 = 1 x 2² + 2 x 1² = 6/2 = 3

NaCl = 1 x 1² + 1 x 1² = 2/2 = 1

Thus, a tri-valent cation (AlCl3) promotes Agglomeration on a ratio of 6 times that of NaCl with a valence of one. The ratio of the tri-valent AlCl3 to the divalent Ca++ is three times as effective in producing agglomeration.

As stated earlier, counterions from the electrolyte solution are attracted to the negative surface of the colloid, producing a charged system called the Double Layer. If the negative charge is adequate, some counterions will become firmly attached, producing the Stern Layer.

This compact Layer partially neutralizes the charges of the electrolyte solution and the electrostatic attraction on the colloid, thus forming the diffuse part of the Double Layer.

The Zeta Potential is affected by the ‘bulk stress’, a term referring to the effect of total inorganic electrolytes in a solution on a colloid.

High concentrations of anions will force a proportionate degree of adsorption on the colloid until the monolayer is achieved. In a highly cationic solution, the increased ‘bulk stress’ will free van der Waals Forces, thus resulting in agglomeration.

Six electrolytes were used in an experiment: three anionic, having valences of1, 2 and 4, and three cationic, having valences of 1, 2 and 3. As the colloid enters the solution, it registers approximately-30 , which represents a negative Zeta Potential resulting in a fair degree of dispersion.

In concentrations of 1 to 10ppm the more strongly cationic electrolytes cause the colloid to lose its negative charge and move toward agglomeration. The electrolytes with a 1:1 ratio effect the colloid to move toward a higher Zeta Potential, as do the anionic electrolytes, creating greater dispersion. As the ionic concentration is increased, the initial effects are enhanced until a plateau is reached, whereupon the colloid becomes increasingly influenced by cationic forces and eventually agglomerates.

The degree of dispersion or coagulation is dependent upon the valence: the higher the valence, the greater the effect on the colloid.

Non-ionic surfactants can adsorb onto the colloids, creating Steric Hindrance, which interferes with ionic mobility and thus with Zeta Potential. Sugar and alcohol are non-ionic surfactants.

Amphoteric surfactants are capable of liberating either anionic or cationic potentials, and are sometimes referred to as ‘zwitterions’. Amino Acids in an acid medium may supply cations or anions in an alkaline medium.

Colloid stability is a result of adsorption. Following is an example of the use of a surfactant (in this case, a detergent) to enhance adsorption and raise Zeta Potential, thereby producing dispersion.

If the system is then serially and geometrically diluted with distilled water 1:2, 1:4, 1:8, etc., to halve the detergent concentration at each dilution, desorption of the adsorbed anion will occur. This returns the system to within 3mv of its initial Zeta Potential. Thus, desorption closely approximates adsorption.

Desorption will prevail as long as the monolayer from the ‘bulk stress’ is maintained. This illustrates why an anionically-dispersed system cannot be diluted without materially lowering the Zeta Potential.

Until this point, we have been describing systems that are free of applied mechanical agitation. Colloid solutions are responsive to agitation as counterions from the Double Layer re-enter the solution and alter Zeta Potential.

Chapter 11:

ZETA POTENTIAL—

A DIFFERENT PERSPECTIVE

Blood is a colloid system consisting principally of several plasma proteins, several electrolytes, and three formed elements: erythro-cytes, leukocytes and platelets.

Nature favors a negative charge; therefore, the intima of the vascular tree is anionically charged as are the formed elements of the blood. According to Albritton, the average Specific Conductance of human blood is 12,000 SC, with a normal variation of perhaps 3,500 SC at 9:00 a.m. to 35,000 SC at 7:00 p.m.

Expressed in terms of Zeta Potential, 35,000 SC equates to approximately-5 , which is coagulated and unstable. The average, based on 12,000 SC, would be approximately-14mv, slightly anionic and on the threshold of coagulation.

It is the state of dispersion or discreteness of the formed elements within the slurry that assures optimum vascular function. As in any disperse system, the Electrophoretic Mobility of the colloids, or formed elements within the blood plasma is influenced by the ionic concentration and pH of the system, as well as the valence of the ion. Human blood contains 19 electrolytes: 8 essential and 11 non-essential. There are 4 anionic and 4 cationic essential electrolytes; 3 anionic and 8 cationic non-essential electrolytes.

The anions of the blood plasma are Chloride, Carbonate, Phosphate and Sulfate. They are primarily responsible for the maintenance of the bulk stress in support of intravascular dispersion. Chlorine, Fluorine, Iodine and Bromine are referred to as the Halogens. They belong to a group of diatomic, anionic surfactants affecting diverse systems.

The cation Sodium and the anion Chlorine represent the major electrolytes. Aluminum, Calcium and Sodium Chloride are commonly understood substances represented as 3:1, 2:1 and 1:1 electrolytes.

The normal range of Total Dissolved Solids of plasma electrolytes equals approximately 9 grams/liter, including both essential and trace elements, which is structured to average no more than 12,000 SC.

The normal pH of the blood falls in the 7.35—7.40 range. In ranges above or below the normal, Amino Acids as Amphoteric surfactants may supply needed ions in responding to the demands of homeostasis.

In alkaline slurry, anions will be produced, while an acid slurry will liberate cations. The Alkaline Reserve mechanism (discussed in detail in Chapter 8) is a dominant formula in the utilization of amino acids to support homeostasis.

The three major fluid compartments are the vascular tree, the interstitial or extracellular spaces, and the intracellular spaces. For the most part, blood plasma and interstitial fluids have the ability to interchange ions rapidly whereas intracellular ions are not readily exchanged.

If the ionic concentration of the plasma increases to more than 290 milliosmhos, one half of the excess cations will migrate into the Extracellular Fluid (ECF) where they are stored in an effort to relieve the Hypertonicity. When the plasma returns to normal os-molarity, the extra electrolytes, which were stored in the Extracellular Fluid, will re-enter the plasma, eventually to be removed by the kidneys.

If, however, the ionic concentration of the plasma remains elevated, the cationic migration will continue until the Extracellular Fluid is also hypertonic. At this point, the body will make water available to flow into the area of high concentration in an effort to dilute the solution.

Edema is the accumulation of Interstitial Fluid resulting from high ionic concentration. The constant motion of the blood is essential in preservation of fluidity. The concept that lack of motion of blood is associated with coagulation dates back at least to Aristotle. It is essential to maintain discreteness of the formed elements of the blood in order to insure unimpeded flow and thus, coagulation.

The characteristic clotting of blood when removed from the body makes electrophoretic analysis impossible. However, analysis of the urine provides a reasonably accurate indicator of the dissolved solids in blood. Urine is the result of continuous filtration of blood through the kidneys. The primary objective is to save essential electrolytes.

Na+, K+, Ca++ and Mg++ are all cationic, totaling approximately 3.6 grams. Cl^-, HCO3^-, HPO4^-and SO^-, are all anionic, totaling approximately 5.5 grams for a combined ideal total of approximately 9 grams per liter of blood. See Exhibit 4 (Essential Electrolytes in Human Plasma).

Selective tubular resorption assures recycling of these essential electrolytes and the minor minerals, whose total weight approximates 11 to 12 mgs. Other non-essential minerals become a filtration energy gradient against which the kidneys must work.

The Total Dissolved Solids or dissociated mineral salts in a solution can be determined through a Specific Conductance test. Depending upon the number of ions available and the resulting flow of current, it is possible to quantify the Specific Conductance of a given solution with its concentration of salts.

Particle size and measurement are familiar to colloidal scientists, but Zeta Potential is less widely understood. The application of Zeta Potential is particularly important in determining the behavior of particles in the size range below a micrometer. Because Zeta Potential is related to the surface charge of the particle, it is fundamental in the influence of stability and interaction with electrolytes.

When any particle is immersed in liquid the interface becomes electrically charged. The charge can only be measured via the electric field created around the particle. The surface charge is normally characterized in terms of voltage at the particle surface (the surface potential). The Zeta Potential occurs at a distance from the surface and will be different from the surface potential.

The basic method for measurement of Zeta Potential is Elec-trophoresis. Scientists (including Pharmacists) are far more familiar with this method than most Physicians because of its application to the separation of macromolecules.

Particle electrophoresis is a similar phenomenon. The particles in a liquid medium are placed in an electric field; if charged, they will drift within the field—positive particles toward the negative and negative particles toward the positive.

Particles carry a thin layer of ions. The surface separating the stationary medium from the moving particle and its bound ions and solvent is called the surface of hydrodynamic shear, and the Zeta Potential is the potential at this surface. Zeta Potential is determined by measuring the drift velocity of the particle in an electrical field of known strength. The value lies within the range of ±100 for most systems immersed in a liquid.

One of the major uses of Zeta Potential is to study the interaction between colloids and electrolytes. Ions of charge opposite to that of the surface (counterions) are attracted to it, while ions of like charge (co-ions) are repelled from it; thus the concentration of ions at the surface are not the same as those in the bulk of the slurry. The accumulation of counterions near the surface reduces Zeta Potential.

The major application of this colloid-electrolyte study is to understand stability and flocculation. The earliest understanding of this Zeta Potential phenomenon was known as the DLVO (Deryaguin-Landau-Verwey-Overbeek) theory, which states that the stability of the colloid is a balance between attractive van der Waals Forces and the electrical repulsion due to the surface charge.

If Zeta Potential falls below a certain level, the colloid aggregates (due to the attractive forces). Conversely, high Zeta Potential maintains a stable system. In highly technical fields, the exact point at which electrical and Van der Waals Forces exactly balance is known as the critical flocculation concentration.

Zeta Potential measurements in a specific system are dependent on the chemistry of the surface and how it interacts with the surrounding environment. This requires a basic understanding of pH and ionic strength on the part of the treating Physician. Please note the following:

• The particle has a surface with a negative charge (Mono-layer)

• In the water near the particle there is a layer of mostly positive ions (The Bulk Stress)

• After the layer of positive ions is a layer of mostly negative ions (The Diffuse Layer).

• As distance from the particle increases, the mix of positive and negative ions reaches the equality of the bulk fluid

• Ions are equally distributed in the outer circle

• Movement of ions in the two layers at the surface of the particle (the von Helmholtz Double Layer) is greatly restricted.

The Zeta Potential is the difference in the charge between the bulk and the particle with its attracted ions.

New technology is rapidly advancing the understanding of Zeta Potential. Laser Dopplers are now used to shine a beam through a suspension across which an electrical field is superimposed. Light reflected from the particles gives location and time so that velocity can be calculated.

To review:

• Colloids that do not agglomerate naturally are called stable

• Most particles in water are negatively charged and surrounded by counterions

• Colloidal solids have very large specific surfaces

• If colloids can be brought sufficiently close together, they will join to form larger particles under the control of van der Waals Forces, and then flocculate and precipitate.

• Removal of colloids involves destruction of the stability of colloids, thus allowing them to coagulate, forming a larger particle and settling at a faster rate.

• All colloids possess electrical charges with various signs and magnitudes.

• If electrodes from a direct current are placed in a colloidal solution, the particles migrate toward the pole of opposite charge at a rate in proportion to the potential gradient in the solution. This is called Electrophoresis.

• The mechanism controlling stability of hydrophobic and hydrophilic particles is known as Electrostatic Repulsion.

• Surface charge may be established by preferential adsorption of ions (usually H+ or OH-) from the dispersion medium.

• An electrolyte is a substance that dissociates into ions in solution and becomes electronically conductive.

• Electrostatic Potential is created by a ‘halo’ of counterions surrounding each colloid.

• van der Waals Forces are a function of the molecular structure of a particle.

• Colloids are classified according to their affinity for the dispersing medium: Lyophobic and Lyophilic colloids.

• The surface of the particles in most hydrophobic colloids has a tendency to acquire electrical charges as a result of preferential adsorption of ions from a solution

• The above-referenced electrical charges will strongly hold a thin rigid layer of ions of water to form an inner fixed layer (the Stern or von Helmholtz layer).

• Counterions will be attracted to form a new outer diffused layer. The electrical charges surrounding colloidal particles form a ‘double layer’. The interface between the two layers is the ‘shear plane’.

• The difference between the charge of the particle and the body of the solution determines the charge potential of the colloid

• The Zeta Potential is the potential difference between the bulk solution and the shear plane at the envelope of water moving the particle

Physicians and Surgeons trained in Manipulation Therapy understand well the increased electrical flow of segments of the spinal column—Cranio-Sacral and Thoracic-Lumbar—and the segmental control of the Sympathetic and Parasympathetic Systems that control homeostasis and maintain Electrophoretic Mobility of formed elements.

In effect, manipulation is instrumental in allowing full afferent and efferent flow that brings about change of flow at the point of lesion. A full appraisal of Dr. Still’s axiom ‘The Rule of the Artery is Supreme’ demands that we understand the electrolytic forces responsible for homeostasis.

With Osteopathic Manipulation and a thorough understanding of particle behavior in the blood slurry (including the concept of Zeta Potential), D.O.’s now are in the singular best position to give full meaning and full facility to Dr. Still’s axiom. Much of what we write is fully understandable and usable by Osteopathic Physicians, who are uniquely poised to carry to the American public the solution to The Wheel of MisFortune (discussed in detail in our next book—10/99).

Chapter 12:

DIET AND CARDIOVASCULAR-

RENAL DISEASE

The mineral content of the daily input of foods and liquids is of the greatest importance in maintaining health. This, after all, is the source of all the anions and cations, which, as electrolytes, power the electrophoretic activity of the blood system. See Exhibit 5 (Anions and Cations).

Through careful selection of food and drink relative to mineral content, it is possible to manipulate and control to a high degree the dispersion or coagulation of the formed elements.

When viewed in the light of Zeta Potential, the crux of the present epidemic of Cardiovascular-Renal Disease seen in this country appears to result from three major sources:

1) The excessive input of mineral salts into the human system.

2) The inversion of normal Sodium/Potassium ratios in foodstuffs through processing.

3) The gradual overloading and eventual overwhelming of the kidneys due to ingestion of excessive mineral salts.

A major factor contributing to the presence of excessive mineral salts in our food supply lies in the basic misconceptions and lack of knowledge on the part of the Food and Drug Administration concerning the physical chemistry of food processing.

Although the FDA limits certain chemical additions to food to 1.0% of the amount demonstrated to be without harm to experimental animals, they permit virtually unlimited use of hundreds of chemicals that they classify as GRAS (Generally Recognized As Safe).

Sodium Chloride is an example. If one ingested 2 liters of ocean water (60,000 SC) within a 48-hour span, death would follow due to Intravascular Coagulation.

The high ionic concentration of cations lowers Zeta Potential resulting in agglomeration of the formed elements. Other similar inorganic salts would be equally lethal. Lower concentrations are also lethal, but they require a longer period of time.

Foodstuffs cannot maintain a garden-fresh taste when simply canned or processed hours after harvesting. Food processors attempt to mask the deficiency by adding salt (NaCl) to produce optimum flavor. Being inexpensive as well as an excellent food seasoning, NaCl has become the most frequently used additive known.

This increase in NaCl contributes to the inverted Sodium/ Potassium balance consistently observed in processed food. Biochemistry does not explain why nature grows substantially all foodstuffs with Potassium dominating the ratio; it simply appears to be the pattern around which Earth’s creatures thrive.

While Sodium and Potassium compounds are similarly monovalent ions, their stability characteristics differ, as Hofmeister pointed out in 1888. Taking the most charitable view, perhaps the FDA is not aware of the consequence in the blood slurry resulting from this change in Na/K ratio.

The only hope we have to minimize the ill effects of this needless inversion is to avoid as much as possible these processed foods and to increase the daily intake of Potassium.

Frequently prescribed forms include Potassium Gluconate, Acetate, Bicarbonate, Citrate and Chloride. The use of these supplemental Potassium salts improves the electrolyte balance essential to cardiovascular renal function.

Any rational approach dictates that food processors should not be permitted to materially alter the natural Sodium-Potassium ratios of foodstuffs. Studies show the extreme changes in mineral solids contents of common foodstuffs due to processing.

The Sodium in bacon, bran flakes, canned beef, self-rising flour, olives, pretzels and sausage is extremely high and are some items responsible for the high intake of mineral salts in this country, now approaching 20 grams per day per person.

This is about twice nature’s intended load on the kidneys. It is evident from these tables that even with care in selection, it is virtually impossible for one to consume present day foodstuffs usually found in the aisles of our grocery stores without ingesting excess Sodium Chloride and also creating an un-natural Sodium-Potassium balance.

Only government regulations to control the processing and proper labeling of foodstuffs could correct this.

The prospects are not bright.

The Sodium-Potassium ratio in processed foods is reversed, with Sodium now dominating by a factor of 3:1 (75:25).

The increase in Sodium in the processed products as contrasted with the fresh is five-fold (75:14).

While the emphasis has been primarily on avoidance of Na+ ions in foods, other cations with higher valences, such as Aluminum, Lead, Mercury, Zinc and Cadmium, to name a few, are inadvertently contained in processed foods and drinks. This constitutes another source of cations responsible for ‘salting out’ of plasma formed elements, and leads to impairment of renal function.

The Specific Conductance of human blood is approximately 12,000 SC. Urine varies from about 10,000—60,000 SC (the latter value representing an extremely dangerous condition).

As a result of the typical American diet, the kidneys are often operating against a gradient of mineral salts as high as 60,000 SC; their original mineral salts load from a natural diet would be in the range of 7,000—12,000 SC.

The Specific Conductance of clarified ‘fresh’ vegetables averaged 7,500 SC, which is well below the normal value of human blood (12,000 SC).

The processed food values, however, averaged about 17,500 SC, which is about 50% higher than human blood. The mineral solids content of the foods increased due to processing by a factor averaging 2.6, increasing the renal workload by the same factor.

In addition to foods, there remains another major source of pollution by mineral salts: America’s processed drinking water.

The Environmental Protection Agency protocol is followed by all water plants throughout America’s cities and small towns. It calls for certain mineral salts to be added to precipitate solids, resulting in a less turbid solution.

They are not in the least related to the needs of the human body; instead, they are selected almost entirely for their efficiency in controlling the erosion of cast iron pipes. Aluminum Sulfate, a tri-valent coagulant, is used extensively in water treatment and is passing into our drinking water.

Research has shown that Cardiovascular-Renal Disease could be significantly allayed by employing appropriate electrolytes in mineral-free distilled or Reverse Osmosis water.

The difference between the light and heavy loads is that under conditions of lower mineral solids input, the kidneys filter the blood to 12,000 SC, and discharge the urine into the bladder with little or no concentration required. Under these conditions, their principal function is to retain the mineral salts needed to maintain proper electrolyte balance in the blood system.

With high mineral solids input, the kidneys have difficulty holding down the blood minerals to 12,000 SC, and with the limited quantity of water usually introduced into the system, it is necessary for the kidneys to concentrate these salts and produce urine in the Specific Conductance range of 20,000—30,000 SC, occasionally higher.

In these situations, dissolved solids may be stored in the Interstitial Fluid space until the Specific Conductance is reduced. Toxic electrolytes, such as Pb⁺⁺ may invade muscle and bone tissue for storage.

An individual producing urine averaging 25,000 SC, representing 20 grams of mineral salts intake, and a daily urine volume of 1.2 liters, forces the kidneys to concentrate the blood minerals 1:2 (12,000—25,000 SC) before discharge into the bladder.

By drinking 1.2 liters of additional water, which doubles the urine output, the Specific Conductance of the urine will remain at 12,000 SC. At this value, there is no need for any concentration of the blood minerals before they are discharged to the bladder. In other words, the ‘load’ on the kidneys has been removed.

We advise all patients to drink at least a pint of mineral-free water before breakfast, lunch and dinner. The daily output of mineral salts obviously must equal the daily input if the internal environment is to remain constant. The input occurs principally at mealtimes, say 7 a.m., 12 Noon and 7 p.m., a range of 12 hours.

Most of the water-soluble salts of foodstuffs go into the blood stream rapidly and appear within 30 minutes as increased Specific Conductance of urine.

Thus, when not overloaded, the work day of the kidneys does not exceed 15 hours, leaving a 9-hour night period for the kidneys to trim up and bring the electrolytes of the blood stream into proper balance. The night urine from healthy kidneys should have relatively low Specific Conductance.

With debilitated kidneys, the story is changed. If the kidneys are unable to discharge mineral salts at a sufficient rate to hold blood minerals at a level approaching 9 grams, they must then operate overtime, up to a 24-hour day! With elevated input of minerals the universal pattern, by the time most of us reach middle age our kidneys are working 24 hours a day for many years.

There has been much research of a statistical as well as experimental nature that incriminates salt (NaCl) as the principal causative agent in Cardiovascular-Renal Disease.

Under the law of Zeta Potential, it is not the salt per se, but the high-energy gradient against which the kidneys must work; namely concentrating blood electrolytes at 12,000 SC to urine electrolytes at 25,000—30,000 SC.

Apparently, the FDA took it for granted that if two kidneys could pump 10 grams of mineral salts to waste per day without difficulty, they could also pump 20 grams. Thousands of athletes can run the 100-yard dash in 12 seconds, but no one in 6. They all can jump 5 feet, but none 10. The logic in permitting the doubling of mineral salts in food and water was not only presumptuous but also completely erroneous and dangerous.

The patient with Cardiovascular-Renal Disease must have an intimate knowledge of what takes place in his own internal environment. Like the diabetic, this patient must strive to be his/her own best physician and to assume a high level of responsibility in the management of the condition.

Chapter 13:

CALCULATING SPECIFIC

CONDUCTANCE

A very useful formula for estimating the amount of mineral salts discharged daily by kidneys is:

SC x volume x factor = Output of salts in grams

Although each ion will carry its own specific amount of current depending upon valence and other considerations, remember that for liquids in the concentration range of urine and blood, each micromho is equal to one-half ppm of equivalent Sodium Chloride.

The Specific Conductance of urine in micromhos in thousandths is determined. The volume of urine in liters/24 hours is recorded.

A factor of 0.65 is the multiplier to equate the Total Dissolved Solids with gravimetric Sodium, or conversion of Specific Conductance to grams.

To evaluate urinary function, or healthy kidney output vs. debilitated kidney output:

Factor the total plasma volume in pints by multiplying the body weight in pounds x .075; divide by two to convert to quarts.

Multiply the plasma volume in quarts x dissolved solids in urine/ quart in grams.

180 lbs. x .075 = 13.5 (approximately 14 pints) or 7 quarts plasma

7 quarts plasma, with 9 grams of electrolytes per quart = 63 grams of electrolytes total, or the ideal.

With 20,000 Specific Conductance of urine (previously calculated), the urine solids equated to 19.5 grams x 7 quarts = 136.5 grams of electrolytes, an overload of 73.5 grams (136.5—63.0).

From 10:00 p.m.—4:00 a.m. urine volume was 300 ml (about maximum), but the salts removed amounted to 2.9 grams. This indicated the kidneys could not produce Specific Conductance values better than 15,000.

By drinking 500 ml of water (4:00—4:45 a.m.), 2.3 additional grams of salts were removed in 45 minutes. This is a rate increase 6 times above the grams of salts excreted in 6 hours with low water volume. Had those kidneys been able to bring blood minerals into balance during the period of sleep, they would have done so. From 4:00 a.m.—7:15 a.m., with ample water available, these kidneys discharged 4.6 grams of salt.

The subject represented in the above, a male weighing 170 lbs. with a blood volume of 7.5%, or approximately 12.7 lbs. (5.8 quarts or 5.5 liters) with 9 grams of minerals/liter, would have approximately 50 grams of total mineral salts.

The 4.6 grams of salts discharged from 4:00 a.m. to 7:15 a.m. actually represented an excess of 9%. An excess of 30-40% of mineral salts produces massive Intravascular Coagulation, which threatens your very life.

Chapter 14:

ANIONIC SURFACTANTS IN

CLINICAL MEDICINE

The potential of Anionic Surfactant Therapy in the control of thrombi in clinical medicine has not been generally recognized for numerous reasons. Colloidal chemistry (surface chemistry) is very much an interdisciplinary subject with certain areas of Physics and Chemistry most prominent.

Owing to the complexity of most colloidal systems, the subject of particle behavior within a given slurry is not readily evaluated with exactness.

This lack of precision and its interdisciplinary nature could be responsible for an unjustifiable tendency to neglect colloidal science during undergraduate academic training.

As we approach the subject from a teleological viewpoint (everything has a definite purpose) and alternate between simple man-made inorganic systems and sophisticated organic natural systems, it is obvious the same basic principles apply to both.

Zeta Potential brings order to the vast present knowledge of practical and theoretical colloid stability. Specifically, Zeta Potential represents a basic law of nature and it plays a vital role in all forms of plant and animal life. It is the force that maintains the discreteness (particles do not touch) of the billions of circulating cells that nourish the organism.

The stability of simple inorganic man-made systems is governed by these same laws. Above all, Zeta Potential stresses the real importance of di-, tri-and polyvalent ions and their overwhelming control of coagulation when associated with the cation, or their control of dispersion when associated with the anion.

The four areas of attack are:

1. Etiology of Intravascular Coagulation

2. Prevention of Intravascular Coagulation

3. Thrombolysis through Anionic Surfactant Therapy

4. Living wisely with those entities not preventable or treatable.

Cardiovascular-Renal Disease is rampant in America. Presidents of the United States who die shortly after leaving the White House, Mayors of our great cities, countless political leaders are (with equal discrimination) stopped in the prime of life, their Death Certificates reading ‘Coronary Infarction’, as do the Death Certificates of our parents, relatives and friends.

Billions are spent in a failing attempt to by-pass an occluded vessel essential to life function. America’s physicians support the current drive to alleviate this carnage, they themselves succumbing to the ineffective approach to the control of Cardiovascular-Renal Disease by surgery.

It matters not to most Americans that the acute entity he/she is suffering is shared by 1.2 million others. What does matter is what has caused this medical problem and how can it be prevented, treated and reversed.

Conventional wisdom assumes many factors in the etiology of Cardiovascular-Renal Disease, including the following:

Atherosclerosis	Atheromas
Cholesteralosis	Lipidemia
Triglyceridemia	Silent Ischemia
Thrombosis Emboli

Fully recognizing that the entities described above do in fact interfere with vascular Laminar Flow, it is of such magnitude one must realize there has to be more to the solution than 75% vascular obstruction commonly believed to be the apex of tolerable interruption of flow.

Americans are blitzed daily with what appears to be the logical etiology of vascular insufficiency … narrowing of the vessels from a variety of selected reasons, the critical interruption site (localized Intravascular Coagulation) to be bypassed.

Chapter 15:

THE CONCEPT

Modern patients use with ease such terms as coumadin, heparin, diuretics, beta blockers, anti-hypertensives, even anticoagulants; the latter representing another of medicine’s classically unscientific terms, having subjective implication but without mathematical accuracy or support. How far can cells be anti-coagulated? Zeta Potential provides a mathematical measure.The stability of a colloid system or emulsion is dependent upon adsorption of ions or polymers from the suspending liquid called the ‘bulk stress’.

Substantially all colloids, both organic and inorganic, are electronegative when suspended in distilled or tap water in low ionic concentrations, in the pH range of 5 to 10. The Zeta Potential of such systems generally ranges from-14 to-30, the range of oscillating discreteness.

Proteins fall into this category, but they become less electronegative with decreasing pH, reaching a zero charge in the pH range of 2 to 5, the range of massive agglomeration.

Ingestion of foods void of toxic electrolytes supplies man with essential anions and cations.

No group of chemicals are classified as toxic until they reach too much.

It appears mandatory that any Physician hopeful of ‘permitting no harm’ to his/her patient, of necessity will have to know the

1) therapeutic dose

2) toxic dose

3) lethal dose

Zeta Potential values less than-14 usually represents the onset of agglomeration. A plateau region, marking the threshold of either agglomeration or dispersion, exists from about-14 to-30 . Values more electronegative than-30 generally represent sufficient mutual repulsion to result in stability (particles that do not touch).

The Environmental Protection Agency has listed 70,000 substances within the ecological system (Chemical and Engineering News). The Atomic Table lists 109 elements found in the makeup of the earth.

Nineteen of these elements comprise the elements essential to life. Their composition, atomic weights, valences and pH are salient factors in controlling Dilatancy and Thixotrophy (Dispersion and Fluidity).

For assured stability, each colloid must retain its complete discreteness with no agglomeration.

Such discreteness may be assured by:

Adsorption on the colloid of an anionic electrolyte to create strong mutual repulsion. Such adsorption can come from the ubiquitous anion from oxygen in the water, labeled the universal solvent for its quick dispersion of small particles in size range of a true colloid (less than one micron), yet a wider range in diameter is used in addressing colloids and suspensoids.

Adsorption of a strongly hydrated hydrophilic protective colloid, such as gelatin, on a larger hydrophobic colloid. In this case, the affinity for water exceeds the mutual attraction of adjacent particles.

Adsorption of a non-ionic polymer of sufficient chain length to create Steric Hindrance, to prevent two particles coming close enough to join. This method is widely employed for emulsions.

When coagulation occurs (desired or undesired) Zeta Potential must be reduced or rendered less electronegative, thus lowering the forces of mutual repulsion.

Short range van der Waals Forces of attraction are responsible for particle agglomeration that usually occurs in the Zeta Potential range of 0 to +3 . Massive agglomeration is aided by long-chain polymers to provide mechanical bridging, in addition to Zeta Potential control.

Colloids can be photographed. Colloid suspensoids are often prepared from dry powders. If not agitated, there is a decided tendency for materials to remain caked. If Zeta Potential is above-35 to-45, no amount of stirring will generally form any aggregation.

With proper viewing methods you can readily differentiate spheres, plates, rods or needles and mobile bacteria. Spheres remain constantly in view. Platelets ‘blink’ as they rotate and periodically expose a thin edge for light reflection. Highly mobile bacteria are evident. Many appear alternately bright and dim as their sides and rounded ends are reflected.

FORMS OF ENERGY

With the exception of gravity, all energy is categorized as Electro-magnetism, which is reduced to anionic and cationic energy. Anions are negatively charged units. Cations are positively charged units. Two particles preferentially charged negatively will repel each other.

All particles in a given slurry so negatively charged disperse each other and are thus ‘livated’. Stephen Hawking, author of A Brief History of Time, calls this ‘levity’.

The antithesis of levity is precipitation. Particles behave in a slurry under the influence of the anion (particle adsorption) via mutual dispersion, while the opposite tendency toward precipitation is referred to as ‘salting out’.

Herein lies the basic concept for control of Intravascular Coagulation of the colloids and suspensoids of the plasma.

Zeta Potential controls the stability of aqueous systems and has been developed by graduated, detailed procedures with systems of increasing complexity starting with silica, clay, carbon, latex, milk, albumin and then blood.

Nature abhors particles in the 200—2,000 range, for it is well known that in a matter of days these often agglomerate to form clusters of less than 1 micron in size, which then enlarge no more. Remember: colloidal stability is a result of adsorption. With proper techniques and interpretation of curves, Zeta Potential can be employed to measure adsorption accurately.

For example, the anionic household detergent ALL when added to a dilute 4,000 (8,000 SC) suspension of Kaolin in tap water, will show the formation of a monolayer at peak dispersion, occurring at a surfactant dose of 800ppm. The Zeta Potential will be elevated from-12 to-45 . This represents good dispersion and is easily plotted.

If the system is then successively diluted with distilled water 1:2, 1:4, 1:8, etc., to halve the detergent concentration at each dilution, desorption of the adsorbed anion will occur. This returns the system to within 3 of its initial Zeta Potential. Thus, desorption closely approximates adsorption.

Keep in mind that desorption will prevail so long as the mono-layer from the ‘bulk stress’ is maintained. This illustrates why an anionically dispersed system cannot be diluted without materially lowering the Zeta Potential.

The anions of the blood plasma are responsible for dilatancy (dispersion)—Chlorine, the Carbonates, the Phosphates and the Sulfates. The first two are monovalent anions; the second two are polyvalent anions.

Di-valent cationic surfactants are on the order of 75 to 90 times more coagulative than the same amount of monovalent surfactants. Tri-valent cationic surfactants and di-valent cationic surfactants are coagulative in the same ratio.

The effect of ‘type’ and ‘concentration’ of electrolytes on colloid stability is germane to thrombolysis through anionic surfactants. The four mentioned anions are primarily responsible for the maintenance of the anionic ‘bulk stress’ in support of intravascular dispersion, essential to Laminar Flow of plasma colloids. Generally referred to as the essential (macro) electrolytes, occurring in human plasma at the homeostatic constant, refer to Exhibit 4 (Essential Electrolytes in Human Plasma).

These represent the most precious elements of the universe in that they are responsible for life and from the beginning have demanded they remain relatively constant. Any deviation challenges the homeostatic mechanism and invites Electrolytic Imbalance, generally a constant in deviation from health.

The reference above represents mg./Liter of electrolytes. Calculation of total essential electrolytes equates to liters of plasma x 3589 to ascertain plasma cations/L and x 5494 for total anions/L.

Plasma volume can be ascertained by multiplying body weight x .075. For example, I weigh approximately 180 pounds. 180 x .075 = 13.5 pints of blood in my body. You will note Na+ and Cl^-represent the major electrolytes. I call your attention to the importance of valence and pH in the evaluation of essential plasma electrolytes, etiologically related to plasma cell dispersion in health and its antithesis, Intravascular Coagulation, in the distortion of normal flow.

Minor blood minerals are just that, at first impact; yet, closer scrutiny will overwhelmingly indict the minor minerals as etio-logical to a wide range of diseases found in patients occupying our hospitals and clinics.

Perhaps here is the timely place to emphasize surplus inorganic minerals are causal to more illnesses than deficits; though acknowledging that the deficits are endocrine-system related and will be discussed at a later time under the heading of endogenous pathological entities secondary to endocrine malfunction.

Our discussion continues with the problems related to Cardiovascular-Renal Disease.

Anyone familiar with elementary chemistry will recognize the term ‘salting out’. Medically speaking, this is referred to via a multitude of general terms such as Intravascular Coagulation, agglomeration, plasma cell clumping, blockage, infarction, deep venous thrombosis, pulmonary emboli, silent ischemia, atherosclerosis, plaque, all correct in an etymology sense, but for this writing we believe each of these terms could be refined with accruing advantage to our knowledge.

The ‘salting out’ efficacy of an electrolyte depends on the tendencies of its ions to become hydrated. Thus, cations and anions can be arranged in the following lyotrophic series of approximately decreasing ‘salting out’ power:

As discussed previously, we can arrange electrolytes via valence as follows:

3:1, 2:1, 1:1, 1:2, 1:3, 1:4

Clark’s arrangement omits most of the trace minerals (Al+3, Pb+ , Hg+ , Cad+ , Zn⁺⁺, found plentifully in most potable drinks, and therefore, in human plasma and urine by iatrogenicity.

Chapter 16:

LIQUIDS: UNIVERSAL SOURCE

OF SUBSTANCE ABUSE

Water is the chief food of survival. Life exists but a few days without it. Approximately 70% of the human body is HO. It is the chief vehicle for mobilizing the essential and trace elements of the human body. It supplies an OH^-radical for dispersion of many colloids. It regulates temperature and numerous other essentials to health. To delineate all of these would be superfluous.

Of urgent interest is the impulse to check out the statement that ‘all water is not the same’. New water cannot be made. What water is here has been here since the beginning. When you hear an admonition that water on planet Earth is seriously polluted, our advice is ‘listen up’.

Particle behavior in water has been discussed but in-depth inquiry is germane into how such water pollution comes about, and what is the individual’s responsibility to him/her self and others.

Standard texts state as much as 90% of all pollutants enter the body via water. When listing pollutants you must include viruses, bacteria and substances (i.e., chemicals). Prior reference has alluded to the toxic and lethal doses as simply ‘too much’ as the critical point.

Obviously, the 70,000 substances admitted by the Environmental Protection Agency (EPA) are at high priority and low expectancy for effective management of our ecology.

The Environmental Protection Agency has admitted that water will not be cleaned up by government effort, the solution being an individual responsibility. Rivers, lakes, streams, aquifer and oceans are resident places for elements of the universe on the move.

Sizable organic loads due to decaying algae, plankton and aquatic vegetation (not to mention human waste) exists as organic loads in the form of discrete solids.

Recall, discreteness is due to electronegative Zeta Potential, small size, and low specific gravity.

There exists a true symbiosis between organic raw water colloids and the aquatic micro-organisms, particularly bacteria. A colloid remains discrete and suspended (via Zeta Potential) until it has fulfilled its final useful purpose, serving as food supply for bacteria.

In this process, Zeta Potential is lowered, permitting particles to aggregate due to van der Waals Forces. Eventually, coarse agglomerates are formed, which then settle in accordance with Stokes Law. The colloid is removed from aqueous suspension and provides ‘room’ for this endless process.

Indeed, the settled particle is still part of a greater biological cycle, because as bottom sludge of lakes and oceans, it then undergoes anaerobic digestion in its overall cycle from organic matter to inorganic matter.

It behooves us to understand this process: Zeta Potential is lowered > van der Waal Forces aggregate > Coarse granules form in accordance with > Stoke’s Law > Sludge undergoes anaerobic digestion > From organic to inorganic matter

I digress here in support of clear understanding of the behavior of inorganics and organics through Zeta Potential. Basic foods are generally classified as organics, which through the ‘three D’s’ (Digestion, Deamination, Decay) organics are reduced to inorganics (the true source of calories) that are then reduced to the final common denominator of electrolytes, anions and cations. More on this later.

Returning to the most important food: water… . Total dissolved inorganic solids are measured through Specific Conductance. Inorganic solids are synonymous with electrolytes. Electrolytes are anionic and cationic.

Fifty years ago I was taught the atom was the smallest object known to man. It had a positive (proton) charge within and one or more electrons on its periphery. The electron (anion) could not further be divided. The Proton (cation) was centrally located, and likewise could not be divided further.

Murray Gell-Mann, Nobelaureate circa 1968, has taught the proton indeed can be further divided into sub-atomic particles and given such strange names as eight-fold ways, quarks, heptanes, ins, outs, held together by gluons. Heady material, indeed!

If sub-atomic particles from the cationic charge exists, and I certainly am not questioning this thesis, perhaps the ubiquitous ‘free radical’ is cationic in nature and therefore offers some explanation as to how free radicals exist and do what is generally ascribed to be destructive to tissue systems.

The anion, on the other hand, is not further dividable and is properly labeled the electron.

Liquid solutions harboring electrolytes are suffering from lack of concern among government officials, physicians and scientists. Chlorine, Bromine, Fluorine and Iodine (the Halogens) comprise a group of anionic surfactants affecting diverse systems. In addition to the Carbonates, the Sulfates and the Phosphates, they become the elements essential to animal life. All are anionic; all contribute to colloidal control through Zeta Potential. Proper use, per os and intravenous, these anionic surfactants support colloidal discreteness and form the basis of thrombolysis in clinical medicine.

Chapter 17:

CARDIOVASCULAR-RENAL

MALFUNCTION

Prevention of these entities obviously lies in the understanding of the etiology:

Ingestion of cationic electrolytes are toxic in excess of 3,589 milligrams (3.5 grams) per liter of blood. Such electrolytes are measurable via blood and urine—techniques described elsewhere through Specific Conductance.

Avoidance of fluids not known to have low Total Dissolved Solids (TDS) approximating 7,000—8,000 in vegetables and fruits. It is not uncommon for the average American to consume 20,000 of minerals per meal. Lethal ocean water at 60,000 SC, via two quarts of ingestion, would prove fatal within 48 hours, the result of massive Intravascular Coagulation secondary to Cationic Hypersalenemia.

Absolute avoidance of the tri-valent Aluminum cation found in America’s water treatment systems. You would not drink tap water if given visual support of the sediment in one quart of water precipitated to show the Total Dissolved Solids therein. A later discussion of renal effort combined with cardiac output will bring proper focus to your understanding. Cardiovascular problems MUST be widened to ‘Cardiovascular-Renal Disease’.

Iatrogenic sources of cations must not be overlooked. I do not prescribe any medication per os, or topically (such as deodorants) containing Aluminum IN ANY AMOUNT.

In excess of 90% of all drugs listed in the Physician’s Desk Reference (PDR) have the potential to divert homeostasis. The culprit: the cation. Later we will discuss the homeostatic mechanism responsible for therapeutic doses of anions and cations essential to health.

Obviously, Harvey Wiley, MD, was right about Aluminum and other cationic surfactants. The food industry is poorly regulated, the government approving many elements within the GRAS list that few expect to be corrected within our time, if ever. If you can find a copy, Wiley’s book (History of a Crime Against the Food Law, 1929) makes fascinating reading. A Chemist, he became the Director of the Department of Agriculture.

Patient education becomes paramount. With 20 million who CANNOT read, 200 million who WILL NOT read and 1/2 million physicians who will not or cannot advise you, it becomes a Herculean task. Given 100,000 physicians (probably Generalists) who can/will teach, however, the problem is not insurmountable.

Each must become his/her own best teacher/doctor/legislator.

I personally am relying on the Generalist with ‘wide angle vision’ as opposed to the Specialist with ‘tunnel vision’.

In recent months, I am encouraged by the inquiry by Internal Medicine specialists who are generally depressed. They have to refer their Cardiovascular-Renal patients for high-tech procedures and big-ticket items. This, especially, becomes critical to an efficacious personal health problem given the solution to thrombolysis in clinical medicine through anionic surfactants, in contra-distinction to Angioplasty or invasive high-tech procedures equivalent to by-pass surgery.

More than 10,000 patients, accompanied by the statement of more than 275 POST by-pass patients who belatedly underwent Thrombolysis through anionic surfactants are offered in support of this concept.

PLEASE SPARE ME the accusation that such cases are but anecdotal and suffer from lack of double-blind techniques. Agreed. Where are those ALIVE who would knowingly permit themselves to take the placebo?

Moreover, where are those SURGICAL programs operating with past experience of double-blind protocol?

If you understand that cations in excess of 3.5 grams per liter is etiological to Intravascular Coagulation, then prevention becomes the #1 priority. Distilled or quality Reverse Osmosis water is used exclusively by our patients. Foods high in cationic sources, i.e., Lead, Mercury, Aluminum, Zinc, Cadmium and the trace minerals, are highly suspect. See elsewhere for liquids, foods, vitamins, carbohydrates, fats and mineral sources of toxicity.

A true blood specimen that sustains a constant Zeta Potential once aerated or shed does not exist.

Previous experiments clearly depict colloidal agglomeration under the influence of the cation. Colloidal Minusil (± 30mv) is readily dispersed at that Zeta Potential. Only 3ppm or 6 SC is necessary to take Zeta Potential to 0.

Aluminum is the most plentiful element found in the earth’s crust. Elsewhere we have shown that Aluminum is known universally to be toxic at the level of 5ppm with Zeta Potential from 0 to +3.

Note that CaCl (a cationic surfactant 2:1) using the colloid Minusil (-30mv) as the starting point, note that-25 Zeta Potential occurs with 100 concentration of electrolytes. At 12,000 , Zeta Potential is 0. This is the physico-chemical mathematics of agglomeration.

Continuing at-30 Zeta Potential using NaCl in tap water (not distilled water), 1,000ppm is slightly elevating of Zeta Potential to-40 . KCl:NaCl depicts two 1:1 surfactants, which reach-10 Zeta Potential at a concentration of 10,000ppm.

Elsewhere you will understand the mathematics of equating Total Dissolved Solids in a urine sample to gravimetric equivalency of Sodium. Moreover, you will learn elsewhere how to use Specific Conductance of urine to calculate Total Dissolved Solids via micromhos extrapolated to fix the Intravascular Coagulation point via ‘bulk stress’.

Referring to the von Helmholtz/Smolukowski Stability characteristics, note that agglomeration occurs within a very narrow range at-10 to-15mv . See Exhibit 6 (von Helmholtz/Smolukowski Table). Therefore, given a ‘bulk stress’ of low Zeta Potential, plasma cell agglomeration is quick and certain.

Now turn your attention to the numerical distance from-16 to-30mv , the threshold of delicate dispersion. Additional colloidal dispersion is found at-81 to-100 mv, providing extremely good stability.

Earlier it was stated any electrolyte is toxic or lethal when the level is ‘too much’. Cationic electrolytes 3:1 Aluminum, 2:1, CaCl2 and 1:1 KCl/NaCl are cationic surfactants contributing significantly to colloid agglomeration. Keep in mind anionic surfactants CAN produce agglomeration when electrolyte concentration reaches ‘too much’.

100ppm of KCl/NaCl concentration raises Zeta Potential to – 50mv and then levels off, unchanging, until 500ppm of electrolytes, at which the Zeta Potential elevates no more. Here Zeta Potential lowers rapidly with greater bulk stress reaching-8 Zeta Potential at approximately 10,000ppm concentration.

Also note that 1:1, 1:2 and 1:3 electrolytes illustrate that any dispersing electrolyte or poly-electrolyte is capable of producing two identical values, one before the peak (or plateau) and another past the peak.

Tetrasodium Pyrophosphate is a 1:4 anionic surfactant and as such represents maximum dispersion of any plasma electrolyte. Note 100ppm drives the Zeta Potential to -70mv when coagulation occurs.

Thus, we have seen the agglomerating effect of cationic surfactants 3:1, 2:1 and 1:1 and the effect of anionic surfactants 1:4, 1:3, 1:2 and 1:1.

Generally, cationic surfactants used in pharmacology are ‘downers’ while the anionic surfactants are ‘uppers’.

Perhaps rather overly simplified with reference to maintaining homeostasis at an imaginary fulcrum, we should place the extremely heavy downers (Serotonin) at the left of the fulcrum and the Cat- echolamine, Norepinephrine, Ephedrine and Amphetamines at the right of the imaginary fulcrum.

The Endocrines

All foods are external surfactants. Approximately 41-45 nutrients are found in foods. Basic classification of foods are generally recognized as:

Proteins	Fat
Carbohydrates	Vitamins
Minerals	Water

Proteins, amino acids, peptides, enzymes, digestion and deamination are factors responsible for reduction of complex proteins into amino acids, which upon hydrolysis liberates the anion within an alkaline medium, and the cation within an acid medium. Proteins become less electronegative with decreasing pH when pH-Zeta Potential curves cross the line of the charge in the pH range of 2 to 5.

About 20-24 amino acids have been recognized as constituents of protein molecules. All are soluble in water except Tyrosine and Cystine. Most of the acids contain one free Amino (NH2) group, and one free Carboxyl (COOH) group. Some have two amino groups to one carboxyl group; others have one amino to two carboxyl groups.

Decarboxylation follows microbial decomposition whereby CO2 is driven off as a gas, leaving the hydrogen. Since Zeta Potential reflects the net electronegative charge at the surface of a particle, it is obvious that elimination of the COOH radical must render less electronegative the net charge on the particle.

Other pathways, resulting in the elimination of the electronegative radical, serve to explain the lowering of Zeta Potential on suspended colloids resulting in settling or precipitation. Coagulation is generally effected when proteins are dropped to the pH range of 4 to 6.

Many micro organisms are capable of reducing pH by acidification and via elaboration of long-chain polyelectrolytes, or one which is cationic. It is interesting that through prolonged biochemical activity, nature never reduces the average Zeta Potential of organic colloids to zero, not even as close as-8.

Chapter 18:

THE TERRAIN

Claude Bernard’s classic remarks defining homeostasis as those internal constants that support and maintain life was a source of irritation to the founder of microbiology, Louis Pasteur. Legend has it the two renowned scientists clashed for much of their lives: Bernard stressing homeostasis and Pasteur saying disease came from bacteria.

Shortly before he died, Pasteur admitted Claude Bernard was right: the microbes do not mean anything; everything depends on the terrain’.

The terrain supplies the basics of cellular growth. Within man, such specialized cells form, mature, and fulfill their function in accordance with availability of the nutrients. The primary nutrients (some lists go as high as 41) and the essential primary and trace electrolytes (19 in number) appear to be the easiest to measure and observe. Language simplifies their identity, function and duration.

AMPHIPATHIC REAGENTS

They number four and are Surfactants.

1. Anionic Surfactants (the electron) that is available in distilled or non-distilled water (H2O). The OH^-radical, anionic and ubiquitous since water covers more earth surface than land.

Nature’s choice is the only plausible reason for her preference of the anion as the ion adsorbed to a colloid (particle). Preferential adsorption, therefore, represents a natural phenomenon and is responsible for utility of the anion in supporting the Electromotive Force (EMF) or Electrophoretic Mobility.

2. Cationic Surfactant, the result of ionization when the compound is ionized by hydrolysis, positively charged, and is the counter-ion to the anion.

The smallest mass, the atom, has a positive charge in its nucleus and the anion (electron) orbiting the proton. The consensus is the anion cannot be further divided, while the proton has further division, represented by such terms as ‘quarks’, ‘strange ups and downs’, etc. The cation represents a positive charge, counter to the anion.

3. Non-ionic Surfactants, such as sugar and alcohol, do not carry a current, function with respect to a colloid by obstructing mobility via Steric Hindrance.

4. Amphoteric Surfactant. This form of energy, so fuzzy to many, bears the name ‘zwitterion’. This surfactant supplies both the anion and the cation. Availability of use is of either ion depending upon pH.

The OH^-or anionic ion is alkaline-dependent. Conversely, the cation portion of the element is acid-dependent. The source of amphoteric surfactants are amino acids.

It would appear all the itemized sources of nutrients are reduced to amphipathic reagents. Amphipattos: open pathology—found in 27 foods consumed worldwide. Such proteins, fats, carbohydrates, vitamins, minerals and water are but suppliers of the forces of life embodied within the function of the amphipathic reagents.

Bernard’s Thesis certainly is overwhelming. Complexity is now reduced to simplicity. The Electromotive Force (EMF), Electrophoretic Mobility, Electrophoresis (all generally used interchangeably) is powerful in supporting his theory of homeostasis. He describes homeostasis as those internal constants supporting life—the beginning and maintaining of life itself.

The electrons found in the 19 electrolytes of human plasma reduce themselves to mathematical constancy. The electrolytes are subject to change with the speed of light, since it is generally recognized life is the electron that had to exist in any plasma supporting life.

Interestingly, plasma is described as ‘confined space inclusive of electrons’. Outer space is a plasma. Inside of a fluorescent light there exists a plasma. However, for these purposes, blood plasma is our subject.

Dishomeostasis exists when deviation from the normal exists.

Now that Physics has given us some basics, let us look at the basis in mathematics in order to evaluate the beginning of homeostasis. Actually, we are evaluating the terrain.

The obvious value of blood plasma with its amphipathic reagents looms as the major variable aspect of the terrain, their availability to perpetuity becoming paramount. These internal constants are variables under the stresses of the environment and constitute the real challenge of medicine.

If medicine is reduced to science and science is reduced to Physics, the umbrella of mathematics, astronomy, chemistry, biology, physiology, psychology and sociology, then medicine is indeed a challenge.

An attempt to reach an understanding of these scientific disciplines may be at the heart of the tendency to specialize rather than enter general practice.

Some think that specialization (loss of scientific integration) is a natural sequelae in the history of medicine. Indeed, in all industry there is aversion to scientific integration.

Personal experience, temperament, or a general feeling of inadequacy may push the physician in either direction.

Strong writings can be found on both sides of this issue. No question, statistics support the high cost of medicine, the largest outlay of dollars pointing to high-tech procedures and big ticket items, spending more on fewer.

Prevention is talked about but never integrated into most medical practices, and certainly is outside the scope of insurance company reimbursement. As Huey Long said, ‘Nobody ever builds a statue to those who prevent anything or saves us money’. Yet, the idea of prevention plays well in Peoria, or for that matter, anywhere in America and at all economic levels.

Many think this is the basis of the current political revolution occurring in the U.S.

It is important to understand the cause, prevention and treatment of dishomeostasis. The terrain is not sustained. It is imperative the host keep in mind the cation ratio 35% to the anion ratio 65% of the total surfactants, fixed at 9 grams per liter of plasma.

Relatively less important and likewise often overlooked is Glucose, BUN and Sodium mEq in establishing the Osmolarity Index. Therefore, the best tools for evaluating the terrain contain more than those found studying the Osmolarity Index and blood gases.

It is important to keep in mind the ratio of anions to cations within the slurry, the important presence of sugars and alcohols, and obviously, the amino acids (amphoteric sources of the zwitterions). These surfactants, according to the valences and kind, become the physician’s best tools for maintaining good health (homeostasis or terrain) and the resultant ability to avoid pathology.

An understanding of normal electrolytes, their valences and specific conductivity, offer simple reference, accurate and reliable when judging a regimen designed to correct dishomeostasis.

Chapter 19:

MY PERSONAL FOUR HORSEMEN

Like an aging dowager who refuses to bow to the ravages of time, the classic pillared mansion stood regally at the top of the letter T where West Third and Denison Avenue junctures in the city of Columbus, Ohio.

This was Doctor’s Hospital heritage, the beginning of a thread that would run so true through decades of service to the people of central Ohio, and more specifically, would weave the fabric cloaking hundreds of young eager Interns whose privilege it was to sojourn old Radium Hospital where it all began.

Holding the lantern of light for so many of us to see was a quartet of Physicians, Drs. Frank Spencer, J. O. Watson, Harold Clybourne and Ralph S. Licklider. The Four Horsemen of my generation and profession-to-be. Harry Struhldyer, Elmer Layden, et al, were to live in fame, but these four men gave us more than a thrill on a few Saturdays of a college football career. THESE giants gave us a PROFESSION.

My good friend, Lee Funk Jr., of Standex Laboratories in Columbus, gave me the family tie to the Rinehart Radium Hospital, sire of Doctor’s Hospital. Lee Funk Sr., is a former President of the Ohio Pharmaceutical Association. Daughter Barbara would become the bride of Dr. Eddie Rinehart, who would distinguish himself as a Psychiatrist at the world-famous Menninger Clinic in Topeka. Lee would lead me to an introduction to the first of the fabulous four, Dr. Frank Spencer.

It was September, 1949, and I had an acceptance into the Philadelphia College of Osteopathy and Surgery Class of 1950. At age 34 each year’s delay was just that—a year of wasted time.

Lee prompted action: ‘Let’s go see what we can do … I know a man who might help us’.

And so we were off and running to the office of Dr. J. O. Watson who was understandably busy somewhere in a meeting.

Without pause, Lee was leading me to another door with a name lettered in gold on glass: Dr. Frank Spencer, Internist. My protestations were to no avail. Wet hands were extended and an interview began.

Lee: ‘Can you get my friend into Medical School THIS year?’

Dr. Spencer’s cool analytical mind, borne of years of clinical experience, bore down on me.

‘Where did you get your pre-Med?… . What kind of grades did you make?… . Do you have financial support for 4 years?… . Why do you want to be a D.O.?’ The questions were fired like bullets.

With trembling hands I extended to him my resume, letters of recommendation, summary of educational and professional experiences and following a brief analysis (to my mind not unlike he was reading a lab report on a critically ill patient!) he spun in his chair, dialed a single digit and changed my life.

‘Get me Joe Peach’ (President of the Kansas City College of Osteopathy and Surgery). My pulse beat an audible staccato within my ears. This was certainly a man of action. Before I could reflect on other crowding thoughts, he barked a greeting.

‘Hello, Joe, this is Frank Spencer in Columbus’. A pause was quickly followed by a brief ‘Pretty good, how is the missus?’, followed by another pause and then he went right to the heart of the matter.

‘Joe, you remember that favor you promised me? Well, I’m ready to collect. I have a young man here who wants to go to Medical School. He’s qualified’… . some of his other remarks were not recorded in my brain, since I was beguiled by his reference to me as a young man! 34 is not young and 2 days past Freshman matriculation is not early when applying for admission to Medical School, each chair available at a 12-1 ratio at that time.

I remember murmuring to myself: ‘I have a chance equivalent to that proverbial snowball in Hades’. You have to bear in mind this is Wednesday, 3 days after the 71 members of the Class of 1949 had convened in Kansas City, Missouri and I am still in Columbus, Ohio. Suddenly I realized Dr. Spencer was addressing me.

‘How soon can you get to Kansas City?… . You’ve got a place if you can get there by Monday morning.’

In the first of many serendipitous events, a student had withdrawn that very morning. I mumbled some statement of gratitude, whereupon Dr. Spencer smacked me on the gluteals and said ‘Get going and don’t let me down—I’ve got a stake in you’.

The 900 miles to Kentucky for my books and personal effects and then to Kansas City would eat up most of my time the next 2 1/2 days.

It would be at the end of my training in 1953 before I would meet the other Horsemen. Again, my friend Lee Funk Jr. would hold the lantern providing the light for me to see.

It was arranged that I would do my Internship at Doctor’s Hospital, although it required a last-minute resignation from Grandview Hospital in Dayton and an agreement worked out to the satisfaction of both institutions.

Choice of practice location loomed high for Kentucky, which did not require Internship. It would give me back another year by allowing early entrance into general practice.

I had never for EVEN ONE DAY considered specialty practice. Among some of my mentors at Kansas City I had discussed pro and con the value of an Internship. Serendipitously, I took the Internship where advanced information had proclaimed there was ‘no better Internship available in our profession than at Doctor’s Hospital’.

Subsequent experiences would not repudiate that statement.

An early rotation into the Orthopedic Department brought me under the tutelage of Dr. Harold Clybourne, head of the Department of Orthopedic Surgery. A no-nonsense personality whose hobby of flying gave him great relief from the onslaught of fractures, spinal surgical procedures and (if I was a typical case in point), the ever-present need to pound some Orthopedic sense into the minds of 13 neophytes masquerading under the flattering name of Intern. A case in point.

On the occasion of this particular day of inviting weather, Dr. Clybourne asked me to join him for lunch. Calm, cool and leaving little to chance, his flying defensiveness spilled over into his patient care and vice-versa. He had a characteristic below the level of consciousness of movement of his eating fork that dangled to and fro from his wrist like a pendulum, unhurried but highly visible.

‘Mac’, he paused to chew, ‘I’m going to be upstairs a few hours today and I want you to look in on a patient who may need a bivalve of a body cast … if he needs it, take care of it’.

An hour later when I caught a glimpse of Dr. Clybourne leaving the Hospital dressed for flying, I realized he didn’t mean ‘upstairs’ at the Hospital—he was going cross-country flying—’up-stairs’.

I rushed to check on his patient. Now you must recall that an Intern is just that. When he said bi-valve I screwed my brow thinking ‘What does he mean by that?’ Famous last words: I’ll look it up!

The patient was indeed in pain. I was knee deep in cast dust, ripping the cast off this patient’s fractured spine when Dr. Clybourne’s office Nurse walked in to see how I was doing. Serendipity again, for without her timely presence and knowledge, a fractured cervical vertebral column would have been minus a plaster cast and I minus some skin off my nose.

For days I hung my head in self-flagellation. His fatherly admonition was constructive, and at the end of my Internship I wrote him a thank you note for his contribution to my knowledge and tutelage in his Department. He lamented he didn’t often get thank you letters.

He occasionally experienced Thoracic and Cervical Somatic Dysfunction in his own spine, and it was an honor to have him ask me to ‘work on my cervicals and dorsals’.

One of his remarks will go with me forever. ‘Don’t forget the laying on of hands—someday someone will show scientifically that energy from the hands of a knowledgeable Physician can boost low energy levels of the diseased and disabled.’

Dr. Harold Clybourne is not gone. He’s somewhere ‘upstairs’—flying.

The chronology or order of discussion of the Four Horsemen is dictated by appearance as they say in the Theater. No attempt is made to prioritize or give top billing.

Next was Dr. J. O. Watson, Surgeon, Author, Lecturer par excellence, member of the Ohio State Board of Medical Licensure, leader, ad infinitum.

He had a keen interest in a Catholic School in New Lexington, Ohio (Perry County)—St. Aloysius. It was my good fortune to follow him by several years and reap the benefits of his ‘holding the lantern’. Not infrequently he would come to New Lexington and his support would provide many opportunities for professional growth. Meanwhile, back at the Hospital, one event occurred that I want to relate.

He was a giant of a man, moving with a physical gait suggestive of a huge pachyderm. Shoulders would weave to and fro as he unhurriedly placed one foot ahead of the other, meandering the corridors of Doctor’s Hospital, (generally wearing a scrub suit of GREEN while all others were WHITE), hands clasped behind him, head and shoulders lowered only to come up to meet and greet any who approached.

It was a few days after I wrote the Ohio Board of Medical Licensure and I had not at this time in life gotten to know him very well. As a lowly Intern I knew my paper would be scrutinized by him, and more to the moment, I was approaching a giant within our profession—alone.

‘Good morning, Dr. Watson’, I offered. ‘Hellooooo, Mac’, he intoned as he came to a halt. ‘Mac, I want to ask you about that State Board question on Fluoride Toxicity. How did you arrive at that answer?’

Fear and trembling encompassed my physical being: I had flunked the Board!

It was a test question, I suppose, designed to get an honest response. Any answer of your own would be given full credit for there was no “THE” answer. Pro-fluoridation or anti-fluoridation was the intent of the answer that divided professionals in 1954 as perhaps now.

I’m not sure what I said—mostly I just did a good snow job since I honestly didn’t know much else to say. I knew the Halogens—Fluorine, Bromine, Chlorine and Iodine were more alike than different. Having been trained in swimming pool management I knew Chlorine was effective at 4ppm against most microorganisms, and that someone had observed that in Ulvade, Texas, school children were free of dental caries secondary to the natural presence of fluoride in their drinking water.

This could support public water fluoridation given accurate control by public water works technicians, but one problem loomed: that of Fluorosis (mottling of the enamel when fluorine exceeded 5 ppm). I had observed this in some military people exposed to excess fluoride in the South Pacific during World War II.

My relief was palpable; he assured me this was a good piece of deductive reasoning and served to point out a primary characteristic of his own make-up I would later come to value. I was on Cloud Nine at his parting remark: ‘I like people with good powers of deduction’.

For nearly 14 years we served on the Licensure boards of the respective states of Ohio and Kentucky. I found his counsel and friendship invaluable. I am doubly pleased we were able to talk a few months before his untimely departure. May the light of his lantern never grow dim. Wouldst there be another like him, for so many among us will miss him and so few among us will beam the light so steadily.

Last, but by no means least, Dr. Ralph Licklider was the only one of the Four Horsemen regrettably I did not keep in close contact with until the end. There were instances of divergent opinions, and as they say in diplomacy, we had some ‘frank discussions’. These discussions were never permitted on my part to stand in the way of my admiration of his surgical skill and therefore permitted no restraints about the great contributions he made to my professional growth and confidence.

With his passage in June 1988, the Fabulous Four were no more.

Fully aware that no one does it alone, a true story follows, untold until now.

In may, 1955, my wife Mary and our firstborn of three months were having lunch in our new home next door to my office in New Lexington. No patients were scheduled until the following day. A huge shadow covered the screen door as a tall, strong father, holding his 16 year old son in his arms, exclaimed: Are you the new Doctor?’.

What my eyes beheld was not pleasant to contemplate over lunch. His anguished, bleeding son had ditched a Jeep and the Jeep had ditched him. His Gala Aponeurotica was 2/5 detached, blood was pan soma (covering his body). Now you have to remember I am but a few months out of Internship and fully aware of my limitations. Acting decisively, I said we’ll have to get your son to a Hospital, and I suggested Doctor’s Hospital in Columbus, 65 miles away.

His father snarled at me with contempt, which to this very day I have not forgotten: ‘You’re a Doctor, ain’t ye?’

The word DOCTOR was so emphatic it was a challenge at best and disgust at the least regarding my decision to refer rather than get to work. I am not a believer in the Supernatural, but I kid you not, Ralph Licklider’s voice came through my ‘headphones’ clearly and audibly! Unhurriedly, with patience and confidence, his voice carried through his face mask.

‘You’ll need to use heavy sutures, maybe 4 or 5 silk. Begin our anchor at the midline midbrow to assure mirror imaging as you follow with 5 or 6 ought interrupted sutures to close in support of tissue approximation. Yes sir, small interrupted sutures preceded by heavy anchor sutures assure good cosmetics. Check for small bleeders and use a mosquito hemostat with or without sutures. Your judgment and a compressive scalp bandage will minimize bleeding. You might want to ice the area.’

2 1/2 hours and an excess of 100 sutures later, his lantern was giving me light.

Recently, the young man, now approaching 40, was in my Cincinnati office. A thin forehead line ran from temple to temple, not much more noticeable than the natural brow line above and below the surgical apposition. Any pride I may have in effect belongs to Dr. Ralph Licklider.

Those of us whose destiny was to stand in the lantern light of these four giants of the Osteopathic profession should count our blessings. Truly, the end of an era.

Chapter 20:

PHYSICIAN, HEAL THYSELF!

I was excited about driving to Pittsburgh for a 24-hour medical conference with a renowned Physician from the West Coast. It was successful, enjoyable and another shined a light for me to see.

The friends who drove had a modern Lincoln as long as a limo. My friend’s lovely wife drove and we sat, lounged, and talked incessantly. She would occasionally remind us to stop; sometimes we ate and many times we did not. For 7 or 8 hours, the back end of the ‘limo’ was my home.

We had taken along good water to drink and did our best to eat as wisely as travel accommodations would support. We all know that the food industry of America has some problems. Obviously, the return trip for the same miles and the same stops occurred in nearly inverse order.

Two days after I returned home I suddenly experienced symptoms that meant the approach of deep venous thrombosis or superficial venous phlebitis. Like flashes of lightening and sufficiently painful to interrupt a thought or action, sharp pains kept returning at intervals of 2-3 minutes. I realized I had a problem.

For many years, we have been saying to our patients that most of our problems are inhibition of antegrade flow of blood. Not so often is it arterial but venous, and venous stasis appears correctly in many diagnoses having to do with deep venous thrombosis or peripheral phlebitis.

My patients and I are well versed in the system of producing antegrade flow, erasing venous stasis and supporting dispersion of the formed elements (red cells, white cells and platelets), all essential and supportive in health.

I had discomfort but it kept increasing in intensity until I could no longer neglect it. We have had many years of helping patients avoid deep venous thrombosis, pulmonary emboli, venous stasis of less intensity and we now know that the etiology is obstruction and such diagnoses as positional edema, superficial venous stasis and/or precipitation or agglomeration of the aforementioned formed elements.

I began an intravenous infusion of applied anionic surfactants. The fluids were normal saline and the surfactants were those essential to return the blood physiology to dissociate the cells that were clumping and interfering with antegrade flow.

These surfactants are a part of the overall plan to correct dishomeostasis, to return the circulation to antegrade direction, and to disperse the formed elements so that the clots and slowed circulation is corrected.

From past experience, we have observed that the anionic essential electrolytes are the Chlorides, Citrates, Carbonates, and Sulfates, all contained in the essential surfactants that maintain dispersionary homeostasis. Usually by the end of 2/3 of the time allotted to infuse the surfactants (approximately 30 minutes) we notice improvement. In my case, I did not have much relief—the electrifying type pain and flashes and involuntary muscular spasms persisted.

I raised the ratio of anionic surfactants and got some relief in another 10 minutes. In reflecting on why I had to raise the medications, I began to have a belated understanding of my own inadequacies: I did not practice what I knew.

As a 180 pound male, I easily calculate that I should have about 7 liters of blood. I also have long known that the number one problem in venous stasis relates to inadequate liquid intake. I also recalled that in the 1950’s, Ivy League colleges found we are usually two liters low in blood volume before we become thirsty enough to think about drinking.

In other words, I was in hypovolemia.

My flashes of discomfort did not leave entirely though it might be 10 minutes between such flashes of pain before I realized I needed more water. We tell our patients repeatedly that the number one problem of disturbance of antegrade flow is hypovolemia, not enough water.

I drank 3 liters of water within 6 hours. It might be important to note here that this constant deficit heads the list of the things that all patients must correct.

Good water to OUR patients is water that has been either distilled or from a competent Reverse Osmosis unit.

We teach that the common problem in America’s circulatory disorders is the pollution that comes with high amounts of cat-ionic electrolytes, primarily aluminum, tri-valent in power, a critical element in the use of precipitating the particles in water so that the water we drink would be potable, generally meaning that we will drink it though unaware that we are still polluting ourselves.

We cannot see the sediment in the bottom of the container or at the bottom of the large containers at the city water works where these chemicals are used (approved by the Federal Government) to produce precipitation so that the supernatent can be siphoned off, pushed through our pipes and into our homes.

The greatest single invention of the 20th Century in my opinion is the development and effectiveness of a Reverse Osmosis water unit that will remove these toxic substances in part responsible for Intravascular Coagulation, Deep Venous Thrombosis, Pulmonary Emboli and Kidney Stones, all components of The Wheel of MisFortune.

Physician, heal thyself.

I made two MAJOR errors: I sat too long and I supported dishomeostasis. Therefore, I drank too little and did not move around enough to produce antegrade flow by contraction of muscles (either walking or standing).

The one lesson to be learned here is that we are all easily able to return to our earlier practices and without full realization that if we are going to stay healthy we have to maintain it by constant vigilance to what we eat and drink.

Yes, I make mistakes too, but I will be more attentive the next time I recline in a ‘limo’ and relax thinking that all I have to do is be comfortable.

Reminder: The next time you take a flight longer than two hours or a car trip of the same duration, remember to stand and move around. Take good water with you and drink it, even though you won’t feel thirsty.

A BEATING HEART

For three decades a chicken’s heart was kept ‘beating’ long after the muscles, bones and feathers had turned to dust. The two scientists, Dr. Alex Carrell and Col. Charles Lindberg and associates, at the University of Chicago, macerated (diced) the muscles of the chicken’s heart, placed them within a large petri dish containing a slurry of distilled water q.s.ed with the essential minerals of life, which trigger cardiac muscle contraction.

They prepared for a long wait. They were not prepared to wait 3 decades, for not much of value would accrue a longer watch. Sooner than expected random twitching, peripherally, then centrally, independent arrhythmia were observed.

In due time with pan wide twitching some areas twitched in unison, soon joined by other arrhythmia contractions, forming a larger mass of myocardial rhythm. In time, all independent contractions ‘beat’ in union.

Years later the tissues continued to contract in unison given adequate electrolytes frequently supplied to the plasma’, defined as any medium to which is added or contains ions and cations in the homeostatic ratio. Sixty years later some observed and learned from this art of ancient research.

At our Seminars for Physicians called ‘Disease Reprieve’, this phenomena is discussed at length, hopefully leading to a better understanding of cardiac myopathy and a more direct approach to the reduction of the most devastating entity known to present day medical care—the etiology and subsequent prevention and reversal of myocardial infarcts and related dysfunction.

The tales of two Physicians six decades later.

In 1995, a plastic surgeon, age 40, performed cardioversion on himself. The chap got a shock from a 110-volt wall socket while repairing a lamp in his examining room. After dragging himself to a heart monitor, he found that he was in rapid atrial fibrillation, ‘with a heart rate of 160 per minute’. Being about to pass out, and with no help at hand, ‘he charged a cardioverter defibrillator and gave himself two shocks of 100 watt—seconds (100 joules). He fell off the table, but sinus rhythm was restored. Subsequent heart monitoring did not show a recurrence of arrhythmia’.

In Cincinnati, another Physician named T. C. McDaniel awakened at approximately 4:00 a.m., with awareness of extremely cold limbs—thighs distally to feet and toes. A quick count of his pulse revealed an arrhythmia appearing as a deficit of antegrade flow supported by loss of pulse every other beat.

Thirty nine beats per minutes indicated Bradycardia and a probable heart block unclassified in the absence of an EKG. The bedroom stabilized, giving time to self analyze vital signs. Chest pain strangely absent, the primary overriding coldness was remarkable.

Long schooled in the vital importance of antegrade flow and essential need for all plasma electrolytes, notably the four basic Cations, my problem loomed large. Living alone and the closest telephone 14 feet away, any option related to getting help appeared slim. I decided to stay in bed, use the bedclothes, my pillow and a light garment within reach to conserve heat.

The heart appeared consistent in throwing blood every other beat and I felt coherent, but not strong enough to reach the phone. Moreover, my associates would be in the office by 8:00 and could come to my apartment above the clinic. Four hours loomed big in this kind of arrhythmia. I knew the formula for righting arrhythmia’s all the way from Wickenback Arrhythmia to acute Tachycardia at 280 b/m or higher.

Last fall a surgeon walked into our Clinic in fibrillation. He weakly greeted me, in one breath saying ‘I hear you can defibrillate tachycardia without cardioversion, which I understand completely arrests my heart rate and we trust to luck that my heart reactivates itself, not trained in Cardiology. I don’t like those odds’.

An IV solution 250 ml of D5/W and an infusion of the essential amphipathic reagents, 80 gtts/min. I went about my clinic duties, pausing to say it might take an hour or less. Within 40 minutes he stuck out his leg in a mock attempt to trip me as I walked by, before he told me ‘I’ve reverted’. I knew it. His sober countenance had dissipated.

His pulse now at normal sinus rhythm, his electrolytes had returned to the proper ratio, anionic to cationic, enabled his kidneys to detoxify a highly cationic slurry on the one hand (the true etiology) and the applied reagents of the intravenous infusion on the other hand, had restored blood electrolytes and homeostasis.

His fear associated with 100 joules to interrupt any cardiac thrust, and trust to luck compared to a return to electrolyte homeostasis via a friendly IV, was readily more acceptable.

Now back to my heart block, still unclassified, but that knowledge is of small consequence. What counts is correcting the Electrolyte Imbalance. In time, a phlebotomist was located, my assistant prepared the formula (an infusion of essential electrolytes), and as they say, the rest is history.

Within 1 hour 15 minutes, my Bradycardia secondary to cat-ionic surfactants or Wickenback phenomena, or heart block or whatever numeral value, was of little consequence.

Until proven otherwise, I work on the theory of Electrolyte Imbalance constitutes the problem and proper plasma electrolytes are the solution.

No EKG, no Cardioversion, no stimulations pericardally (long outdated), no ambulance runs, no ER experience, all likewise someday outdated cardiac procedures.

Which of the two techniques, given a heart block dx or fibrillation would you choose, as a physician or a patient?

I would like to share the story of my own family—six senior citizens from age 70 to 90. Disease Reprieve is behind the longevity of the McDaniel Clan.

We are enjoying the cumulative advantages of a regimen developed to live into the Golden Years without assisted living, electric chairs or a walking cane (with but one exception at age 88 with Emphysema). All siblings drive, are free of frequent visits to their own Physician, with Social Security benefits now approaching a million dollars spanning 110 years of eligibility because we lived longer then the Actuaries predicted.

Cardiovascular-Renal decline takes more than a million lives each year (the majority long before retirement age) for the reason that so little has been done in support of Disease Reprieve.

The average DO lives no longer than our MD counterpart, succumbing to the ravages of The Wheel of MisFortune by age 57.

It is not enough to KNOW the components of The Wheel of MisFortune. You must be vigilant on a daily basis, recognizing the health hazards waiting for you at every turn.

The secret of the Disease Reprieve regimen is simple.

NO MORE HEART ATTACKS

NO MORE INFARCTIONS

NO MORE ARRHYTHMIAS

NO MORE KIDNEY STONES

NO MORE LITHOTRIPSY

NO MORE DEEP VENOUS THROMBOSIS

Chapter 21:

KIDNEY MALFUNCTION

On the subject of kidney stones, you have to realize that everything that is big enough to be a problem had to begin with smaller, less mass, brought together until the size is a problem.

No doubt you have heard Physicians talk about the different kinds of kidney stones that develop. No doubt they have told you that dietary chemicals, chemicals in the ecology, chemicals in solutions (what we drink, eat) all have small particles that have to go through the kidney parenchyma.

You may have heard of Bowman’s Capsules, Henley’s Loops, anatomical parts of the tubules that run through the working part of the kidney. The purpose of the kidney is to throw these particles out of your system once they come into the system through the mouth, breath, drinks, infusions, or any opening.

When particles agglomerate they agglomerate in proportion to the inability of the host to help in the work of removing these particles, these colloids, these items that make bigger particles.

The kidneys are handicapped because the brain is not aware or does not care to do its part in helping the kidneys do their part. It’s well known that every drop of blood in the body has to go through those kidney capsules (tubules) in pursuit of isolating and throwing away particles, chemicals, ions, electrolytes, foreign bodies and throw them away if they are not needed in the overall process of survival.

Obviously, when you consume adequate fluid intake free of chemicals (or particles of electrical energy that play a key role in keeping particles dispersed so that the smaller particles could be eliminated through the ureters that empty into the bladder), the cause of kidney stones is avoided.

High on the list in the cause of kidney stones is eating and drinking chemicals that produce clotting. Particles that are small become larger. In addition, when the volume of the plasma (which is related to the volume of water and liquids that we partake throughout the 24 hour day period) fails to have enough liquid to keep the particles in suspension, it’s easy to see how particles become too big to go through the ureters because of low water volume.

Now that you understand that you need to know a little bit about how to help your kidneys do their work, it becomes highly important that you pay attention to what you eat and drink.

We talk about dialyzing your plasma before the fact, before you eat and drink chemicals in solutions of tap water, the numerous liquids that are sold in the grocery stores and the waters that you drink being polluted with these heavy coagulating chemicals.

It is no different than in the early 1830’s and 1840’s when our ancestors traveled westward inside a Conestoga wagon or riding an animal, or afoot, we had a very important guide whose job it was to keep us from getting into polluted water, and kept us from literally dying because we had so many water holes in the westward trek that were polluted with these same toxic substances that are in our water today.

Involved in the trek westward today, via plane or car, far many more people will get into trouble today without a guide (the Kit Carsons and the Indians, or other individuals who knew the trail westward and how to avoid the pollutants of the ecology).

It is imperative that you recognize the hazards of drinking and eating and yes, even medications, because contained in these foods that we perceive are going to help us and supply us with essential electrophoretic movement of these particles that otherwise would produce a stone, we would have to learn how to keep the plasma liquids highly fluid and containing adequate electrolytes found in a healthy individual by understanding the homeostatic principle of medicine.

Homeostasis literally means ‘stability of man’.

You must consume adequate amounts of water to make it easy for blood particles to flow and for these formed elements (called red cells. white cells and platelets) to be adequately dispersed so they don’t form a clot (or a stone).

Once you have a pain, usually recognized on the right part behind your belt, radiating down the front into the groin, and periodically say 2-5 minutes apart, pain of such excruciating degree it gets your attention! In addition, you do not have to be a Physician to know you have trouble. You may not know that you have been unable to prevent it because you did not know some basics in biology and know how particles behave in a closed system under the influence of the electrolytes.

The treatment is quite simple. You need to hydrate and raise the volume of the blood, which in almost every case is in what is known as hypovolemia or low plasma (water) volume. In the treatment, you need to put in the fluids in greater quantities and hence we use a 5 prong attack to dilute the volume and then dilate the ureters and use surfactants that are going to make particles disperse.

It would require these five prongs to the attack usually within the confines of an office of a competent general practitioner who understands that this is the easy way to get the stone out and avoid invasive techniques like lithotripsy, invasion of the bladder or ureters by instrumentation, thus avoiding more pain and more cost, more disability in a confined hospital setting needlessly.

It is expected and routinely performed in our offices with intravenous infusion of these surfactants that are going to participate in making these particles disperse and medications that are going to dilate elsewhere described so that particles now can move into the bladder and exited by way of the urethra.

It is not unusual to see the stone in the bottom of a strainer when the patient voids under the influence of increased micturation (urination).

It is interesting to note the way a large particle grows from lesser parts into bigger objects, and it’s so simple that it just invites skepticism as to why it is so difficult for this to not have been a part of yours and my knowledge long before now.

Two or more particles when they are forced into their own electrical fields, counter ionic forces produce the beginning of the growth of the object (stone). As they become larger in mass they might take on the appearance of a soft gel and technically speaking, further enlarging to a hard gel and then eventually with the absence of sufficient fluidity, we now reach a mass that will stick together as it passes down the ureters into the bladder and out through the urethra.

The pain occurs when each milking effect commonly referred to as a spasm, pushes the stone too fast because it is too big, and it scrapes or lacerates the lining of the ureters, thus bleeding is often a part of this syndrome.

Alternate, intermittent, disabling pain is a pattern and is associated with this construction of the ureter and its physiological function pushing a drop of urine from the calyx of the kidney into the bladder. Obviously, smooth muscle dilation would help, sufficient analgesics of a strong nature to hide pain, and hydration of the circulatory system by way of intravenous infusions, of half normal saline or 0.9 mg. of sodium chloride per liter of sterile water.

Obviously, if you are diabetic we would prefer not to use Glucose, although many Physicians do. I personally do not like to use Ringer’s Lactate because of high ionic concentration of electrolytes.

In effect, the management of kidney stones is how do you recognize the hazard, the eating and drinking of pollutants that add components to the urine and blood plasma responsible for the agglomeration, ‘salting out’, uroliths, a variety of names all meaning smaller particles coming together producing larger particles.

The question is frequently asked: how long does it take to do this and how much fluid will you use in your intravenous solution?

The answer is whatever is needed.

It has been our experience that 1-2 liters of intravenous infusion, with up to that much per os, you hydrate adequately to dislodge the stone and get relief.

May we repeat: Thus avoiding the big-ticket items associated with lithotripsy, invasive techniques, longer hospitalizations become a burden. We have not found it necessary to hospitalize a patient in 25 years using this concept.

Chapter 22:

THE OSTEOPATHIC

SCHOOL OF MEDICINE

America’s Family Physician. If you have occasion to visit our Medical Clinic, you will find a full-color brochure outlining the concept of Osteopathy. This is must reading for all our patients.

Osteopathic medicine is a unique form of American medical care developed in 1874 by Andrew Taylor Still, MD. Dr. Still was dissatisfied with the effectiveness of 19th Century medicine. He believed that many of the medications of his day were useless or even harmful. Dr. Still was one of the first in his time to study the attributes of good health so that he could better understand the process of disease.

In response, Dr. Still founded a philosophy of medicine based on ideas that date back to Hippocrates, the Father of Medicine. The philosophy focuses on the unity of all body parts. He identified the musculoskeletal system as an essential element of health. He recognized the body’s ability to heal itself and stressed preventive medicine, eating properly and keeping fit.

Dr. Still pioneered the concept of ‘wellness’ 100 years ago. In today’s terms, personal health risks—such as high blood pressure, excessive cholesterol levels, stress and other life-style factors—are evaluated for each individual. In coordination with appropriate medical treatment, the osteopathic physician acts as a teacher to help patients take more responsibility for their own well-being and change unhealthy patterns.

Sports medicine is a natural outgrowth of osteopathic practice, with its focus on the musculoskeletal system, osteopathic manipulative treatment, diet, exercise and fitness. Many professional sports team physicians, Olympic physicians and personal sports medicine physicians are D.O.’s.

Just as Dr. Still pioneered osteopathic medicine on the Missouri frontier in 1874, today Osteopathic Physicians serve as modern-day medical pioneers. They continue the tradition of bringing health care to areas of greatest need.

Over half of all osteopathic physicians practice in primary care areas, such as pediatrics, general practice, obstetrics/gynecology and internal medicine. Many D.O.’s fill a critical need for family doctors by practicing in small towns and rural areas.

D.O.’S and MD’s

Applicants to both D.O. and MD colleges typically have a four-year undergraduate degree with an emphasis on science courses. Both D.O.’s and MD’s complete four years of basic medical education.

After medical school, both D.O.’s and MD’s can choose to practice in a specialty area of medicine—such as psychiatry, surgery or obstetrics—after completing a residency program (typically two to six years of additional training).

Both D.O.’s and MD’s practice in fully accredited and licensed hospitals and medical centers. D.O.’s comprise a separate yet equal branch of American medical care. Together, D.O.’s and MD’s enhance the state of care available in America. However, it is the ways that D.O.’s and MD’s are different that can bring an extra dimension to your family’s health care.

Osteopathic Physicians continue to be on the cutting edge of modern medicine. D.O.’s combine today’s awesome medical technology with the tools of their ears, to listen caringly to their patients; their eyes to see their patients as whole persons; and their hands, to diagnose and treat injury and illness.

Osteopathic medical schools emphasize training students to be primary care physicians. D.O.’s practice a ‘whole person’ approach to medicine. Instead of just treating specific symptoms or illnesses, they regard your body as an integrated whole.

Osteopathic physicians focus on preventive medicine.

D.O.’s receive extra training in the musculoskeletal system—your body’s interconnected system of nerves, muscles and bones that make up two-thirds of its body mass. This training provides osteopathic physicians with a better understanding of the ways that injury or illness in one part of the body can affect another. It gives D.O.’s a therapeutic and diagnostic advantage over those who do not receive additional specialized training.

Osteopathic Manipulative Treatment (OMT) is incorporated in the training and practice of osteopathic physicians. With OMT, osteopathic physicians use their hands to diagnose injury and illness and to encourage your body’s natural tendency toward good health.

By combining all other medical procedures with OMT, D.O.’s offer their patients the most comprehensive care available in medicine today.

Chapter 23:

REVERSE OSMOSIS

Almost daily the media distorts renal (kidney) pathology with regard to the nation’s water supply. Conflicting stories have the average citizen confused and unable to make intelligent decisions. Where can YOU go for the facts and what are the real problems: economical; individual; political?

We all have a ‘right’ to a safe water supply.

Or do we?

In admitting the present economic and political structure is incapable of removing the toxicities within the US water supply, the EPA says ‘each individual is responsible for his/her own H2O system’. Fortunately, the Government, through research grants and other supporting techniques, has made it possible to produce the Reverse Osmosis (RO) module that is effective in removing dissolved solids from fluids.

How did the renal system get into the first paragraph of this chapter about polluted water? Simple!

Cardiovascular-Renal problems are pandemic (out of control). Thousands are awaiting kidney donations for transplants. Millions are overloading their own renal systems for lack of valid information with respect to PREVENTING Cardio-Renal Malfunction.

Every liquid consumed generally contains chemicals. To save the needed chemicals and discharge the non-essential chemicals is a grave responsibility. A competent Physician can measure the Total Dissolved Solids and therefore determine the presence or absence of minerals in excess of the essential and trace minerals found within normal blood plasma. The Physician will refer to these minerals as electrolytes’.

No doubt you are familiar with kidney dialysis, more correctly known as ‘hemodialysis’. This sophisticated technique is widely used and life-extending to thousands of people. The technology of hemodialysis is ‘membrane removal of undesirable electrolytes within the plasma slurry on the one side and replacement of essential electrolytes on the other side’. In effect, Total Dissolved Solids are removed and renal physiology proceeds until the need returns for another ‘dialysis’.

A competent RO unit removes toxic electrolytes. Not all RO modules are the same, however, despite statements to the contrary. RO Units are being marketed everywhere in the USA. It is not enough to imply that water ‘tastes’ better because Chlorine is removed; chlorine is not the problem! ANY chemical produces an unhealthy and life-threatening state when consumed in quantity.

Knowledgeable physicians are expected to know therapeutic doses, toxic doses and lethal doses.

Total Dissolved Solids of all chemicals, essential or non-essential, are the problem. It is not correct to say that one ‘needs’ the minerals in drinking water. The elements essential to life are NOT found in drinking water. They ARE found in foods produced by sunlight, photosynthesis, 6” of top soil and rain. Only distilled H2O or water from a competent RO module can do this with economic feasibility.

Particle behavior within a solution is controlled by well-defined laws of Physics. Famous Physicians have documented particle behavior and clarified the laws of nature governing particle behavior in a solution.

Others have defined colloidal, cellular or electrophoretic mobility (also known as Zeta Potential) for those who will investigate colloidal chemistry. These works span a century of scientific research.

Total Dissolved Solids over and above 9 grams within the Blood Plasma means increased workload for the renal and cardiovascular systems. What you eat and drink elevates unwanted chemicals above the needed 9 grams of electrolytes and can harm you. Their source is primarily through drinking water and many foods and liquids other than tap water.

Water is the universal ‘solvent’. Particle behavior in water depends on the electrons derived from the solution added. All mass can be divided into names too confusing for this discussion (i.e., quarks, hadrons, neutrons, etc.) and their control of particles by dispersion or aggregation are too serious for the non-scientific mind!

With the exception of the decline of the Roman Empire, at no time in the history of man has there been a more critical exposure to toxic elements within the water consumed by the public.

Lead consumption via the public water system has been identified as the reason behind the Fall of the Roman Empire. The elite drank water from lead pipes and the surviving masses who were not polluted were unable to govern. To imply that water in your (or any other) public water system is ‘good water’ or ‘safe water’ is incorrect.

The Federal Government’s protocol for any and all water systems is the use of chemicals to destroy bacteria and precipitate particles to the bottom to assure consumer-approved drinking water. This water is ‘approved’ because it appears clean, clear and without obnoxious odor.

It is almost impossible for any water system to succeed in producing quality drinking water given the present pollution problems.

Chemicals are out of control. The aquifer (underground water) supply is thoroughly polluted to the extent of failure of lower forms of life to adapt to the pollution.

The public is at risk for a lack of information. Spring water, lake or stream water, well water, tap water, rain water, all of which fall through chemically-laden smog over cities, are unacceptable. Mineral water is often ingested out of the misguided information that it supplies ‘needed’ minerals.

The purchase of a RO module system is affordable, effective and available to the public.

A competent RO module will remove Dissolved Solids approaching 2-5 ppm, or 4-10 SC. Triple distilled water cannot produce water less than 2 SC.

As few as 3-5 of Aluminum Chloride can precipitate the body’s blood cells, commonly associated with the formations responsible for Thrombosis or ‘blood clots’ that lead to coronary infarcts and kidney stones.

The awareness of the presence of chemicals within the water supply is known to all above the age of reason. What is needed is accurate information telling you how to clean up the tap water within YOUR home or work place.

The following guidelines will provide this information.

• Never buy a filter or any type of unit reported to be effective without measuring the Total Dissolved Solids in the water coming through the unit. Any unit permitting 10ppm or 20 SC of Total Dissolved Solids or higher is unacceptable.

• Never consume ‘softened’ water, usually installed in the home for better laundering of clothes and body.

• Activated charcoal filters are designed to trap particles (such as feces and dead animals) and is incompetent in stopping chemicals.

• Silver impregnation within the module constitutes a tremendous heavy metal load and is a toxic burden to the system.

• All RO modules are not the same. Size of pores as low as 2 microns or less is needed to block chemicals.

• Instruments to measure Total Dissolved Solids are available to any competent Physician who can assure you of the presence or absence of electrolytes within any fluid tested.

• Dialyzing drinking water BEFORE the fact insures safety and reduces the need for dialyzing your blood AFTER the fact.

You cannot guard against almost certain death via cardiovascular-renal malfunction without basic understanding of the cause and prevention of disease. There must also be a thorough understanding of basic Physics on the part of those trusted to provide guidance in selecting a competent RO module.

Lip service is paid by politicians declaring they’re ‘green’ or ‘environmentally correct’, but the truth is that nothing is being done to correct the problems described throughout this book.

Chapter 24:

WILL YOU BECOME A STATISTIC?

Recently the Golden Years Society published a newsletter that provides graphic evidence of the inability of the medical profession to cure Cardiovascular-Renal disease. After reading this book, you will understand that the reason there is no cure is the lack of understanding of basic scientific principles as they should be applied to medical science.

WILL YOU BECOME A STATISTIC?

Every 33 seconds an American dies of Cardiovascular Disease (CVD). In 1996, more than 959,200 deaths (41.4% of all deaths) had a primary diagnosis of CVD. In contrast, total Cancer-related deaths were 544,728 and AIDS-related deaths were 32,655.

Currently, the American Heart Association estimates 58,800,000 Americans have ‘some form of Cardiovascular Disease’.

Coronary Heart Disease (CHD) caused 476,124 deaths and is the single leading cause of death in America today.

The National Center for Health Statistics reported that if all forms of major CVD were eliminated, life expectancy would rise by almost 10 years. In contrast, if ALL forms of cancer were eliminated the gain would be only three years! 1/6 of people killed by CVD are under age 65.

STROKES killed 159,942 people in 1996, the third leading cause of death. Stroke is the leading cause of long-term disability in the U.S. Of the 600,000 strokes per year, more than 100,000 are recurrent attacks. In the U.S., someone suffers a stroke every minute, and for people over age 55, the rate of stroke more than DOUBLES in each successive decade.

In 1996, 598,000 Coronary Artery Bypass surgeries were performed on 367,000 patients, at an average cost of $44,820 per surgery.

At least 250,000 people a year die of coronary attack WITHIN ONE HOUR of the onset of symptoms and BEFORE THEY REACH A HOSPITAL. These sudden deaths are usually a result of ventricular fibrillation.

How does this translate into dollars? The government estimates the cost of Cardiovascular Diseases and Stroke in 1999 to be $ 286.5 BILLION.

Forcing patients into HMO’s and developing more high-tech procedures is NOT the solution to this problem.

PREVENTION of cardiovascular-renal disease is the answer. We have thousands of patients who can attest to this approach.

A special Press Conference was called on May 29, 1997, to announce the approval by the FDA for the drug Carvedilol, the first new approach to the treatment of heart failure approved by the FDA in 14 years! (credit Columbia-Presbyterian Medical Center). Dr. Packer of Columbia-Presbyterian was quoted as saying ‘New approaches are needed, as heart failure is a life-threatening condition whose incidence in the U.S. has been rising’.

I read with interest that the Pharmaceutical Company that manufactures Carvedilol urged all patients to maintain their existing regimen of diuretics, digoxin and ACE inhibitors.

These medications are never prescribed by any Physician trained by The Golden Years Society. Our Physicians are trained to widen their scope of knowledge from Cardiovascular Disease to Cardiovascular Renal Disease, thus encompassing the many components of The Wheel of MisFortune, studied in detail during our Seminars. We train 5-20 patients per week at our Tuesday night seminars for new patients, many of whom are by-pass survivors.

THERE IS AN ANSWER

The McDaniel Medical Clinic has been successfully treating patients for Cardiovascular Renal Disease during the time the American Heart Association, the FDA, and the Pharmaceutical companies were studying ‘potential therapies’.

Why are the patients at the McDaniel Medical Clinic able to resume active life-styles free of many (or most) of their initial complaints?

Because our patients understand the CAUSE of Cardiovascular Disease, and they understand the importance of food and drink in preventing and reversing CVD.

The average Physician enjoys no greater advantage than his or her patient—dying at an average age 57.

I began studying in earnest when I developed Cardiovascular Disease at age 50+. I am now 85, conduct a full practice, have published two books, lecture frequently and practice what I ‘preach’ to my patients. My own family consists of six brothers and sister 70—93, all in good health and living independently.

Despite public rhetoric, the medical profession knows how to prevent the spread of AIDS. While it commands much political attention, as you read previously, the number of AIDS-related deaths is minimal. Many forms of cancer are also preventable (chemical ingestion, smoking, etc.).

Chapter 25:

A PERSONAL INVITATION

My personal health history is contained in these chapters. Few books written by Physicians acknowledge that many of the ‘healers’ need ‘healing’.

The writing of any book involves the cooperation of many. I would like to thank my patients for their many expressions of gratitude and kind words of encouragement.

Jane Kress, President of Outsource Designs, Inc., took the raw material for this book and turned it into the finished product you are reading.

With a ready smile and cheerful disposition, nurses Joanne Barnhart and Joyce Couch provide care and support to more than 50 patients per day.

Careful reading of this book will teach you how to recognize the hazards of health hidden within the foods and drinkables of daily life, responsible for the destruction of normal cardiac rhythm. Given this knowledge, we now have a solution to the number one health problem: cardiovascular-renal pathology.

I wish I knew a way to condense 30+ years of study and medical practice into a ‘one-size fits all’, easy to understand How To Manual. I wish I knew a way to telescope a four-year course in Colloidal Chemistry into a single chapter—perhaps along the lines of ‘Colloidal Chemistry 101’.

While I have not been successful in the effort to find a shortcut, I HAVE developed a one day Seminar for Patients, designed to show you how to eat and drink properly, how to measure your personal Zeta Potential, and how to reverse the effects of poor diet and liquid intake. We will teach you how to prevent the slow slide into Cardiovascular-Renal Disease.

We sponsor a three-day Seminar for Physicians, studying the principles of Anionic Surfactant Therapy in great detail, allowing you to incorporate this exciting new program into your practice.

The life you learn to save may be your own.

It is indeed a sobering thought that with proper intake of Reverse Osmosis or distilled water containing appropriate electrolytes, irregular heartbeats (including Paroxysmal Tachycardia) can be reversed—without electric cardioversion.

I recently attended two Medical Association meetings, with participants numbering more than 500. I was dismayed to find many of my colleagues in physiological bankruptcy, unable to maintain their practice, desperate to find an answer to their problems.

After all these years, the ‘experts’ are still saying ‘We see a lot of this’ and ‘Let’s just watch it’. There IS a better way.

We welcome the inquiry of patient or Physician for the dates of our Seminars.

T. C. McDaniel, D.O.

Physician and Surgeon of the

Osteopathic School of Medicine

Telephone:	1-888-761-GOLD
Fax:	1-513-761-4542
Email:	TCMDO@Concentric.net

Cincinnati, Ohio

June, 1999

THOMAS C. MCDANIEL, D.O.

Degrees: AB, MA, D.O.

Colleges & Universities:

Eastern Kentucky

George Peabody (Vanderbilt)

Ohio State

Boston University

University of Health Sciences (Kansas City, Mo.)

Voted OUTSTANDING GRADUATE OF THE CENTURY by Eastern Kentucky University (1972)

Past member Kentucky State Board of Health

Past member Kentucky State Board of Medical Licensure (appointed by 4 different Governors)

Past President, The Kentucky Osteopathic Medical Association

Past President, Cincinnati Academy of Osteopathic Medicine

Past President, American Society of Bariatric Physicians Founder, The National Foundation for the Prevention of Obesity (1975)

Founder, The Golden Years Society, Inc. (1996)

Private practice, Cardiovascular-Renal Diseases, Rehabilitative Medicine, Cincinnati, OH (1983—present)

Author: The Wheel of MisFortune

Disease Reprieve

Serial and Geometrie Dilution

Desorption Curves

Exhibit 3

ESSENTIAL ELECTROLYTES

In Human Plasma


CATIONS
Ca++	5.00	100.00
Mg++	1.00	22.00
Na+	143.40	3,280.00
K+	48.00	187.00
TOTAL:	155.00	3,589.00

ANIONS	104.00	3,700.00
Cl-	104.00 3,700.00
HCO3+	27.00	1,650.00
HPO4+	2.00 96.00
SO4+	1.00	48.00
TOTAL:	134.00	5,494.00

Exhibit 4

ANIONS and CATIONS

	BLOOD	RBC	PLASMA	SERUM
ANIONS
Bromine	0.00	0.00	0.00	0.01
Fluorine	0.28	0.27	0.28	0.00
Iodine	0.07	0.00	0.00	0.07
Total	0.35	0.27	0.28	0.08

CATIONS
Aluminum	0.15	0.07	0.46	0.00
Copper	0.93	0.75	1.11	0.00
Iron	0.48	0.00	0.00	0.00
Lead	0,29	0.57	0.03	0.00
Manganese	0.13	0.19	0.08	0.00
Silicon	0.50	0.00	0.00	0.00
Tin	0.22	0.26	0.04	0.00
Zinc	8.80	14.40	3.00	0.00
Total	11.50	16.24	4.72	0.00
TOTAL	11.85	16.51	4.72	0.08

Exhibit 5

Von HELMHOLTZ-SMOLUKOWSKI TABLE

Average Zeta Potential in Millivolts

Maximum agglomeration and precipitation	0	TO	3
Strong agglomeration and precipitation	5	To	-5
Threshold of agglomeration Threshold of delicate dispersion	-10 -16	To To	-15 -30
Moderate stability Fairly good stability	-31 -41	To To	11 -60
Very good stability	-61	To	-80

Extremely good stability	-81	TO	-100

Exhibit 6

HUMAN BLOOD

ELEMENT	BLOOD	RBC	PLASMA	SERUM
Aluminum	0.15	0.07	0.46	0.00
Bromine	0.00	0.00	0.00	0.01
Copper	0.93	0.75	1.11	0.00
Fluorine	0.28	27.00	0.28	0.00
Iodine	0.07	0.00	0.00	0.07
Iron	0.48	0.00	0.00	0.00
Lead	0.29	0.57	0.03	0.00
Manganese	0.13	0.19	0.08	0.00
Silicon	0.50	0.00	0.00	0.00
Tin	0.22	0.26	0.04	0.00
Zinc	8.80	14.40	3.00	0.00

Exhibit 7

Library of Congress Number:		99-91005
ISBN Numbers:	Hardcover	978-0-7388-0572-6
	Softcover	978-0-7388-0573-3
	Ebook	978-1-4771-6393-1